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4-Chloroaniline
| Item number | 673999 |
| CAS | 106-47-8 |
| Formula | C6H6ClN |
| Molecular weight | 127,57 g/mol |
| Quantity | 1X1000MG |
| storage conditions | 4 °C |
| CoA / MSDS | Retrieve CoA Retrieve MSDS |
Price | Please log in. |
Part of Product groups:
Product Variations:
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
 | 675774 | 1X500MG | Please log in. | |
2-Chloroaniline solution |  | 680101 | 1X5ML | Please log in. |
 | 692363 | 1X500MG | Please log in. | |
 | 673999 | 1X1000MG | Please log in. | |
4-Chloroaniline solution |  | 674000 | 1X5ML | Please log in. |
4-Chloroaniline solution |  | 679882 | 1X5ML | Please log in. |
 | 679503 | 1X10MG | Please log in. | |
 | 679504 | 1X10MG | Please log in. | |
 | 679505 | 1X10MG | Please log in. | |
D4-4-Chloroaniline solution |  | 688999 | 1X5ML | Please log in. |
| Safety Data Sheet | according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 02.12.2024 |
| IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING | |
| Product name: | 4-Chloroaniline |
| Catalog No.: | 673999 |
| Relevant identified uses of the substance or mixture | Identified: Laboratory chemical uses: R&D |
| Uses advised against: | HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com |
| Emergency telephone number | HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours. |
| HAZARDS IDENTIFICATION | 2.1. Classification of the substance or mixture Regulation (EC) No 1272/2008 Acute toxicity - Oral Category 3 - (H301) Acute toxicity - Dermal Category 3 - (H311) Acute toxicity - Inhalation (Dusts/Mists) Category 3 - (H331) Skin sensitisation Category 1 - (H317) Germ cell mutagenicity Category 2 - (H341) Carcinogenicity Category 1B - (H350) Specific target organ toxicity — repeated exposure Category 1 - (H372) Acute aquatic toxicity Category 1 - (H400) Chronic aquatic toxicity Category 1 - (H410) |
| Label elements | |
| Pictogram | GHS06 skull skull GHS08 silhouete silhouete GHS09 Aquatic-pollut-red Aquatic-pollut-red |
| 2.2. Label elements Contains 4-Chloroaniline Signal word Danger Hazard statements H301 - Toxic if swallowed H311 - Toxic in contact with skin H317 - May cause an allergic skin reaction H331 - Toxic if inhaled H341 - Suspected of causing genetic defects H350 - May cause cancer H372 - Causes damage to organs through prolonged or repeated exposure H410 - Very toxic to aquatic life with long lasting effects Precautionary Statements - EU (§28, 1272/2008) P260 - Do not breathe dust/fume/gas/mist/vapours/spray P273 - Avoid release to the environment P280 - Wear protective gloves/protective clothing/eye protection/face protection P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor P391 - Collect spillage P403 + P233 - Store in a well-ventilated place. Keep container tightly closed 2.3. Other hazards No information available. This substance does not meet the PBT/vPvB criteria of REACH, annex XIII. This product does not contain any known or suspected endocrine disruptors Chemical name: 4-Chloroaniline EU - REACH (1907/2006) - Article 59(1) - C andidate L is t of S ubs tances of Very High Concern (SVHC) for Authorisation: - EU - REACH (1907/2006) - Endocrine Disruptor Assessment List of Substances: - | |
| COMPOSITION/INFORMATION ON INGREDIENTS | 3.1 Substances Chemical name: 4-chloroanilines; CAS 106-47-8 Weight %: 100 REACH registration number: - EC No (EU Index No): 203-401-0 Classification according to Regulation (EC) No. 1272/2008 [CLP]: Acute Tox. 3 (H301) Acute Tox. 3 (H311) Acute Tox. 3 (H331) Skin Sens. 1 (H317) Muta. 2 (H341) Carc. 1B (H350) STOT RE 1 (H372) Aquatic Acute 1 (H400) Aquatic Chronic 1 (H410) Specific Concentration Limit (SCL):- M-factor, M-factor (long term): - Full text of H and EUH statements see section 16 Acute Toxicity Estimate If LD50/LC50 data is not available or does not match the classification category, the Corresponding conversion value from CLP Annex I, Table 3.1.2 used to calculate the Acute Toxicity Estimate (ATEmix) to classify a mixture based on its components Chemical name: 4-chloroanilines; CAS 106-47-8 Oral LD50 mg/kg: 300 Dermal LD50 mg/kg: 360 Inhalation LC50 - 4 h - dust/mist - mg/l: 2.34 Inhalation LC50 - 4 h - Vapor - mg/l: No data available Inhalation LC50 - 4 h -gas - ppm: No data available This product does not contain any substances of very high concern (SVHC) from the candidate list in a concentration of >=0.1% (Regulation (EC) No. 1907/2006 (REACH), Article 59) |
| Formula | C6H6ClN |
| Molecular Weight (g/mol) | 127.57 |
| CAS-No. | 106-47-8 |
| FIRST AID MEASURES | 4.1. Description of first aid measures General advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required. IF exposed or concerned: Get medical advice/attention. Inhalation If breathing has stopped, give artificial respiration. Get medical attention immediately.Remove to fresh air. Do not breathe dust. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. If breathing is difficult, (trained personnel should) give oxygen. Eye contact Get immediate medical advice/attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Keep eye wide open while rinsing. Skin contact Get immediate medical advice/attention. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. May cause an allergic skin reaction. Ingestion Do NOT induce vomiting. Rinse mouth. Never give anything by mouth to an unconscious person. Get immediate medical advice/attention. Self-protection of the first aider Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination. Do not breathe dust. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Use personal protective equipment as required. See section 8 for more information. 4.2. Most important symptoms and effects, both acute and delayed Symptoms Itching. Rashes. Hives. Coughing and/ or wheezing. Difficulty in breathing. 4.3. Indication of any immediate medical attention and special treatment needed Note to doctors May cause sensitisation in susceptible persons. Treat symptomatically. |
| FIRE-FIGHTING MEASURES | 5.1. Extinguishing media Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Large Fire CAUTION: Use of water spray when fighting fire may be inefficient. Unsuitable extinguishing media Do not scatter spilled material with high pressure water streams. 5.2. Special hazards arising from the substance or mixture Specific hazards arising from the chemical Product is or contains a sensitiser. May cause sensitisation by skin contact. 5.3. Advice for firefighters Special protective equipment and precautions for fire-fighters Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear. Use personal protection equipment. |
| ACCIDENTAL RELEASE MEASURES | 6.1. Personal precautions, protective equipment and emergency procedures Personal precautions Avoid contact with skin, eyes or clothing. Ensure adequate ventilation. Use personal protective equipment as required. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. Avoid generation of dust. Do not breathe dust. Other information Refer to protective measures listed in Sections 7 and 8. For emergency responders Use personal protection recommended in Section 8. 6.2. Environmental precautions Environmental precautions Prevent further leakage or spillage if safe to do so. 6.3. Methods and material for containment and cleaning up Methods for containment Prevent further leakage or spillage if safe to do so. Methods for cleaning up Take up mechanically, placing in appropriate containers for disposal. Prevention of secondary hazards Clean contaminated objects and areas thoroughly observing environmental regulations. 6.4. Reference to other sections Reference to other sections See section 8 for more information. See section 13 for more information. |
| HANDLING AND STORAGE | 7.1. Precautions for safe handling Advice on safe handling Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin, eyes or clothing. Take off contaminated clothing and wash it before reuse. In case of insufficient ventilation, wear suitable respiratory equipment. Do not eat, drink or smoke when using this product. Remove contaminated clothing and shoes. Do not breathe dust. Avoid generation of dust. Handle product only in closed system or provide appropriate exhaust ventilation. General hygiene considerations Regular cleaning of equipment, work area and clothing is recommended. Wash hands before breaks and immediately after handling the product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Do not breathe dust. Take off contaminated clothing and wash it before reuse. Contaminated work clothing should not be allowed out of the workplace. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. 7.2. Conditions for safe storage, including any incompatibilities Storage Conditions Keep containers tightly closed in a dry, cool and well-ventilated place. Keep out of the reach of children. Store locked up. Please refer to the manufacturers certificate for specific storage and transport temperature conditions. Store only in the original receptacle unless other advice is given on the CoA. 7.3. Specific end use(s) Risk Management Methods (RMM) The information required is contained in this Safety Data Sheet. |
| EXPOSURE CONTROLS/PERSONAL PROTECTION | 8.1. Parameters to monitor exposure limits Chemical name: 4-Chloroaniline 106-47-8 European Union: - Austria: H* , skin sensitizer Belgium: - Bulgaria: TWA: 0.3 mg/m3 Croatia: TWA: 0.04 ppm TWA: 0.2 mg/m3 Skin Sensitisation France: - Germany: TWA: 0.06 ppm TWA: 0.3 mg/m3 H* Germany MAK: * skin sensitizer Greece: - Hungary TWA: 0.2 mg/m3 STEL: 0.8 mg/m3 * Ireland: - Italy:- Italy REL: - Latvia: - Lithuania: Sensitizer * Ceiling: 0.3 mg/m3 Luxembourg: - Malta: - Netherlands: - Norway: - Poland: STEL: 10 mg/m3 TWA: 3 mg/m3 * Portugal: - Romania: TWA: 2 mg/m3 STEL: 5 mg/m3 * Slovakia: - Slovenia: TWA: 0.04 ppm TWA: 0.2 mg/m3 STEL: STEL ppm STEL: STEL mg/m3 * Spain: - Sweden: - Switzerland: TWA: 0.04 ppm TWA: 0.2 mg/m3 H* Great Britain: - Biological occupational exposure limits This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies Derived No Effect Level (DNEL) No information available. Predicted No Effect Concentration (PNEC) No information available. 8.2. Exposure controls Personal protective equipment Eye/face protection Avoid contact with eyes. Wear safety glasses with side shields (or goggles). Hand protection Wear suitable gloves. Impervious gloves. The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374. Wear protective Viton™ gloves . Skin and body protection Long sleeved clothing. Chemical resistant apron. Wear suitable protective clothing. Respiratory protection No protective equipment is needed under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required. General hygiene considerations Regular cleaning of equipment, work area and clothing is recommended. Wash hands before breaks and immediately after handling the product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Do not breathe dust. Take off contaminated clothing and wash it before reuse. Contaminated work clothing should not be allowed out of the workplace. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. Environmental exposure controls Do not allow into any sewer, on the ground or into any body of water. |
| PHYSICAL AND CHEMICAL PROPERTIES | 9.1. Information on basic physical and chemical properties Physical state Solid Appearance Solid Colour beige Odour Aromatic. Odour threshold No information available Property Values Remarks • Method Melting point / freezing point 72.5 °C None known Initial boiling point and boiling range232 °C None known Flammability No data available None known Flammability Limit in Air None known Upper flammability or explosive limits No data available Lower flammability or explosive limits No data available Flash point 123 °C None known Autoignition temperature 685 °C None known Decomposition temperature None known pH No data available None known pH (as aqueous solution) No data available No information available Kinematic viscosity No data available None known Dynamic viscosity No data available None known Water solubility 2.2 g/l @ 25 °C Solubility(ies) No data available None known Partition coefficient 1.83 None known Vapour pressure No data available None known Relative density 1.43 @ 20 °C Bulk density No data available Liquid Density No data available Relative vapour density 4.41 None known Particle characteristics Particle Size No information available Particle Size Distribution No information available 9.2. Other information Molecular weight 127.57 Molecular formula C ₆H₆C lN 9.2.1. Information with regards to physical hazard classes Not applicable 9.2.2. Other safety characteristics No information available |
| STABILITY AND REACTIVITY | 10.1. Reactivity Reactivity No information available 10.2. Chemical stability Stability Stable under normal conditions. Explosion data Sensitivity to mechanical impact None. Sensitivity to static discharge None. 10.3. Possibility of hazardous reactions Possibility of hazardous reactions None under normal processing. 10.4. Conditions to avoid Conditions to avoid Excessive heat. 10.5. Incompatible materials Incompatible materials None known based on information supplied. Hazardous decomposition products None known based on information supplied. |
| TOXICOLOGICAL INFORMATION | 11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008 Information on likely routes of exposure Product Information Inhalation Specific test data for the substance or mixture is not available. Toxic by inhalation. (based on components). Eye contact Specific test data for the substance or mixture is not available. Skin contact May cause sensitisation by skin contact. Specific test data for the substance or mixture is not available. Repeated or prolonged skin contact may cause allergic reactions with susceptible persons. (based on components). Toxic in contact with skin. Ingestion Specific test data for the substance or mixture is not available. Toxic if swallowed. (based on components). Symptoms related to the physical, chemical and toxicological characteristics Symptoms Coughing and/ or wheezing. Difficulty in breathing. Itching. Rashes. Hives Numerical measures of toxicity Acute toxicity Component Information Chemical name 4-Chloroaniline Oral LD50 = 300 mg/kg ( Rat ) Dermal LD50 = 360 mg/kg ( Rabbit ) Inhalation LC50 = 2.34 mg/L ( Rat ) 4 h Delayed and immediate effects as well as chronic effects from short and long-term exposure Skin corrosion/irritation Based on available data, the classification criteria are not met. Serious eye damage/eye irritation No information available. Respiratory or skin sensitisation May cause an allergic skin reaction. Germ cell mutagenicity Contains a known or suspected mutagen. Classification based on data available for ingredients. Suspected of causing genetic defects. Carcinogenicity Contains a known or suspected carcinogen. Classification based on data available for ingredients. May cause cancer. The table below indicates whether each agency has listed any ingredient as a carcinogen. Chemical name 4-Chloroaniline European Union Carc. 1B Reproductive toxicity No information available. STOT - single exposure No information available. STOT - repeated exposure Causes damage to organs through prolonged or repeated exposure. Aspiration hazard No information available. 11.2. Information on other hazards 11.2.1. Endocrine disrupting properties Endocrine disrupting properties 11.2.2. Other information Other adverse effects No information available. |
| ECOLOGICAL INFORMATION | 12.1. Toxicity Ecotoxicity Very toxic to aquatic life with long lasting effects Chemical name 4-Chloroaniline Algae/aquatic plants: - Fish : LC50: 1.8 - 3.2mg/L (96h, Lepomis macrochirus) LC50: 11.0 - 16.0mg/L (96h, Oncorhynchus mykiss) LC50: 29 - 49.1mg/L (96h, Oryzias latipes) LC50: 7.0 - 18.0mg/L (96h, Pimephales promelas) LC50: 9.7 - 12.5mg/L (96h, Oncorhynchus mykiss) LC50: =30.6mg/L (96h, Pimephales promelas) Toxicity to microorganisms: - Crustacea : EC50: 0.12 - 0.78mg/L (48h, Daphnia magna) 12.2. Persistence and degradability Persistence and degradability No information available. 12.3. Bioaccumulative potential Bioaccumulation There is no data for this product. Component Information Chemical name 4-Chloroaniline Partition coefficient 1.83 12.4. Mobility in soil Mobility in soil No information available. 12.5. Results of PBT and vPvB assessment PBT and vPvB assessment The product does not contain any substance(s) classified as PBT or vPvB. Chemical name 4-Chloroaniline PBT and vPvB assessment The substance is not PBT / vPvB 12.6. Endocrine disrupting properties Endocrine disrupting properties No information available. 12.7. Other adverse effects No information available. |
| DISPOSAL CONSIDERATIONS | 13.1. Waste treatment methods Waste from residues/unused products Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation. Contaminated packaging Do not reuse empty containers. |
| TRANSPORT INFORMATION | IATA 14.1 UN number or ID number UN2018 14.2 UN proper shipping name Chloroanilines, solid 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2018, Chloroanilines, solid, 6.1, II 14.5 Environmental hazards Yes 14.6 Special precautions for user Special Provisions None ERG Code 6L IMDG 14.1 UN number or ID number UN2018 14.2 UN proper shipping name Chloroanilines, solid 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2018, Chloroanilines, solid, 6.1, II, Marine pollutant 14.5 Marine pollutant P Environmental hazards Yes 14.6 Special precautions for user Special Provisions None EmS-No F-A, S-A No information available 14.7 Maritime transport in bulk according to IMO instruments No information available RID 14.1 UN number or ID number UN2018 14.2 UN proper shipping name Chloroanilines, solid 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2018, Chloroanilines, solid, 6.1, II, Environmentally Hazardous 14.5 Environmental hazards Yes 14.6 Special precautions for user Special Provisions None Classification code T2 ADR 14.1 UN number or ID number UN2018 14.2 UN proper shipping name Chloroanilines, solid 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2018, Chloroanilines, solid, 6.1, II, (D/E), Environmentally Hazardous 14.5 Environmental hazards Yes 14.6 Special precautions for user Special Provisions None Classification code T2 Tunnel restriction code (D/E) |
| REGULATORY INFORMATION | 15.1. Safety, health and environmental regulations/legislation specific for the substance or the mixture National regulations France Occupational diseases (R-463-3, France) Chemical name 4-Chloroaniline 106-47-8 French RG number RG 15,RG 15bis Title: - water hazard class (WGK) highly hazardous to water (WGK 3) Netherlands Chemical name 4-Chloroaniline Netherlands - List of carcinogens: Present Netherlands - List of mutagens: - Netherlands - List of reproductive toxins: - Poland SDS created according to the following Polish regulation: Act of February 25, 2011 on chemical substances and their mixtures (Journal of Laws of 2018, item 143, as amended). Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), establishing the European Chemicals Agency (EC) as amended. regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labeling and packaging of substances and mixtures, as amended. Regulation of the Minister of Health of 10 August 2012 on the criteria and method of classifying chemical substances and their mixtures (Journal of Laws of 2012, item 1018). Regulation of the Minister of Health of 20 April 2012 on labelling packaging of hazardous substances and mixtures and some mixtures (Journal of Laws of 2012, item 445). Regulation of the Minister of Family, Labor and Social Policy of 12 June 2018 on the maximum allowable concentrations and intensities of factors harmful to health in the work environment (Journal of Laws of 2018, item 1286). Announcement of the Minister of Economy, Labor and Social Policy of August 28, 2003 on the publication of the unified text of the Ordinance of the Minister of Labor and Social Policy on general health and safety at work regulations (Journal of Laws of 2003, no. 169, item 1650) . Regulation of the Minister of Health of 30 December 2004 on occupational safety and health related to the presence of chemical agents in the workplace (Journal of Laws of 2005, No. 11, item 86). Act of December 14, 2012 on waste (Journal of Laws of 2013, item 21) Regulation of the Minister of Health of December 30, 2004 on occupational health and safety related to the presence of chemical agents in the workplace (Journal U. of 2005, No. 11, item 86). Waste Act of December 14, 2012 (Journal of Laws of 2013, item 21). Act of 13 June 2013 on the management of packaging and packaging waste, Journal of Laws 2013, item 888). Government statement of September 24, 2002 - European Agreement on the International Carriage of Dangerous Goods by Road (ADR) (Journal of Laws No. 194, item 1629 and Journal of Laws of 2003, no. 207, items 2013 and 2014). European Union Directive 98/24/EC on the protection of the health and safety of workers against the risks related to chemical Observe working materials at work. Permissions and/or Restrictions on Use: This product contains one or more substances that are subject to restrictions (Regulation (EC) No. 1907/2006, (REACH), Annex XVII) REGULATION (EU) 2019/1148 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on the marketing and Use of explosives precursors Not applicable Restricted substance according to REACH Annex XVII: 28. 43. Persistent organic pollutants Not applicable Category for dangerous substances according to Seveso Directive (2012/18/EU) H2 - ACUTE TOXIC E1 - Hazardous to the aquatic environment in category Acute 1 or Chronic 1 Regulation on Ozone Depleting Substances (EC) No. 1005/2009 Not applicable International inventories TSCA Compliant Contact DSL/NDSL supplier for inventory compliance status Contact EINECS/ELINCS suppliers for stock compliance status ENCS Contact suppliers for inventory compliance status Contact IECSC suppliers for inventory compliance status Contact KECL suppliers for inventory compliance status Contact PICCS suppliers for stock compliance status Contact AIIC suppliers for inventory compliance status Legend: TSCA - United States Hazardous Substances Control Act Section 8(b) Inventory DSL/NDSL - Canadian Equivalent to European Existing Substances List/Canadian List of Substances Existing Only Abroad market are EINECS/ELINCS - European Inventory of Existing Chemical Substances Existing Chemical Substances)/European List of Notified Chemical Substances chemical substances) ENCS - Japan Existing and New Chemical Substances IECSC - China Inventory of Existing Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances PICCS |
| OTHER INFORMATION | The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only! |