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4-n-Nonylphenol

Item number677203
CAS104-40-5
FormulaC15H24O
Molecular weight220,35 g/mol
Quantity 1X100MG
storage conditions20 °C
CoA / MSDSRetrieve CoA
Retrieve MSDS
4-n-Nonylphenol

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Catalog No./ CAS No.

Quantity

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2-n-Nonylphenol solution
Concentration: 100 µg/ml
Solvent: Acetone

2-n-Nonylphenol solution

681087
136-83-4

1X1ML

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4-n-Nonylphenol

4-n-Nonylphenol

677203
104-40-5

1X100MG

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4-n-Nonylphenol solution
Concentration: 100 µg/ml
Solvent: Acetonitrile

4-n-Nonylphenol solution

678159
104-40-5

1X1ML

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4-n-Nonylphenol solution
Concentration: 10.0 µg/ml
Solvent: Acetonitrile

4-n-Nonylphenol solution

679657
104-40-5

1X10ML

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4-n-Nonylphenol solution
Concentration: 100 µg/ml
Solvent: Methanol

4-n-Nonylphenol solution

680446
104-40-5

1X1ML

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D4-4-n-Nonylphenol solution
Concentration: 100 µg/ml
Solvent: Acetone

D4-4-n-Nonylphenol solution

676413
358730-95-7

1X1ML

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D8-4-n-Nonylphenol

D8-4-n-Nonylphenol

691897
2733716-95-3

1X5MG

On request

D8-4-n-Nonylphenol solution
Concentration: 100 µg/ml
Solvent: Acetone

D8-4-n-Nonylphenol solution

691914
2733716-95-3

1X1ML

On request

Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 08.09.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:4-n-Nonylphenol
Catalog No.:677203
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
Skin corrosion (Category 1B), H314
Reproductive toxicity (Category 2), H361
Chronic aquatic toxicity (Category 2), H411
Label elements
PictogramGHS05 acid
acid
GHS07 exclam
exclam
GHS08 silhouete
silhouete
GHS09 Aquatic-pollut-red
Aquatic-pollut-red
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram Signal word Danger
Hazard statement(s)
H302 Harmful if swallowed.
H314 Causes severe skin burns and eye damage.
H361 Suspected of damaging fertility or the unborn child. H411 Toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER or doctor/ physician.
Supplemental Hazard
Statements
none
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Formula : C15H24O
Molecular weight : 220,35 g/mol
CAS-No. : 104-40-5
EC-No. : 203-199-4
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
p-Nonylphenol Included in the Candidate List of Substances of Very High Concern (SVHC) according to
Regulation (EC) No. 1907/2006 (REACH)
CAS-No.
EC-No.
104-40-5
203-199-4
Acute Tox. 4; Skin Corr. 1B;
Repr. 2; Aquatic Chronic 2;
H302, H314, H361, H411
<= 100 %
FormulaC15H24O
Molecular Weight (g/mol)220.35
CAS-No.104-40-5
FIRST AID MEASURES4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Consult a
physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Storage class (TRGS 510): Non-combustible, corrosive hazardous materials
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands. Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into
the environment must be avoided.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing
point
No data available
f) Initial boiling point and
boiling range
No data available
g) Flash point 113 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower No data available flammability or
explosive limits
k) Vapour pressure < 1 hPa at 20 °C
l) Vapour density No data available
m) Relative density 0,937 g/cm3
n) Water solubility soluble
o) Partition coefficient: noctanol/
water
log Pow: 5,76
p) Auto-ignition
temperature
No data available
q) Decomposition
temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available
STABILITY AND REACTIVITY10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
Other decomposition products - No data available
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 1.620 mg/kg
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitisation
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Suspected human reproductive toxicant
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
RTECS: SM5630000
In vitro and in vivo tests showed endocrine disruption activity., 4-NP has been identified as a Substance of
Very High Concern (SVHC) and included into the Candidate List due to its endocrine disrupting properties
which cause probable serious effects to the environment
ECOLOGICAL INFORMATION12.1 Toxicity
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 1,4 mg/l - 96,0 h
Toxicity to daphnia and
other aquatic
invertebrates
LC50 - Daphnia pulex (Water flea) - 0,14 mg/l - 48 h
EC50 - Daphnia magna (Water flea) - 0,18 mg/l - 24 h
Toxicity to algae Growth inhibition NOEC - Algae - 0,243 mg/l - 4 Months
12.2 Persistence and degradability
4-NP is stable and strongly adsorbs into soil, sludge and sediment.
A DT50 of 46,2 days (primary degradation) to no elimination after 703 days (depending on linear or
branched isomers ) was observed under anaerobic conditions in sediment.
12.3 Bioaccumulative potential
Bioaccumulation Gasterosteus aculeatus - 16 d
- 4,9 &#956;g/l
Bioconcentration factor (BCF): 1.300
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects
Toxic to aquatic life with long lasting effects.
Available toxicity data for nonylphenol, branched and linear, ethoxylated (4-NPnEO and NPnEO) are
summarized in order to analyze whether or not they rise to an equivalent concern with regard to their
endocrine disruption properties. Short term exposure to 4-NP may result in life time effects in aquatic
organisms.
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber Contaminated packaging
Dispose of as unused product
TRANSPORT INFORMATION14.1 UN number
ADR/RID: 2430 IMDG: 2430 IATA: 2430
14.2 UN proper shipping name
ADR/RID: ALKYLPHENOLS, SOLID, N.O.S.
IMDG: ALKYLPHENOLS, SOLID, N.O.S.
IATA: Alkylphenols, solid, n.o.s.
14.3 Transport hazard class(es)
ADR/RID: 8 IMDG: 8 IATA: 8
14.4 Packaging group
ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
REGULATORY INFORMATIONThis safety datasheet complies with the requirements of Regulation (EC) No. 453/2010.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
Authorisations and/or restrictions on use
p-Nonylphenol CAS-No.: 104-40-5
REACH - Candidate List of Substances of Very High Concern for Authorisation (Article 59).
Equivalent level of concern having probable serious effects to the environment (article 57 f)
ED/169/2012
p-Nonylphenol CAS-No.: 104-40-5
Regulation (EC) No 649/2012 of the European Parliament and the Council concerning the export and
import of dangerous chemicals
p-Nonylphenol CAS-No.: 104-40-5
Regulation (EC) No 649/2012 of the European Parliament and the Council concerning the export and
import of dangerous chemicals
p-Nonylphenol CAS-No.: 104-40-5
Regulation (EC) No 649/2012 of the European Parliament and the Council concerning the export and
import of dangerous chemicals
p-Nonylphenol CAS-No.: 104-40-5
Regulation (EC) No 649/2012 of the European Parliament and the Council concerning the export and
import of dangerous chemicals
p-Nonylphenol CAS-No.: 104-40-5
Regulation (EC) No 649/2012 of the European Parliament and the Council concerning the export and
import of dangerous chemicals
Chemical qualifying for PIC notification.
p-Nonylphenol CAS-No.: 104-40-5
Regulation (EC) No 649/2012 of the European Parliament and the Council concerning the export and
import of dangerous chemicals
Chemical qualifying for PIC notification.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!