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Warfarin sodium

Item number684938
CAS129-06-6
FormulaC19H15NaO4
Molecular weight330,31 g/mol
Quantity 1X250MG
storage conditions4 °C
CoA / MSDSRetrieve CoA
Retrieve MSDS
Warfarin sodium

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Warfarin sodium

Warfarin sodium

684938
129-06-6

1X250MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 15.01.2025
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Warfarin sodium
Catalog No.:684938
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 1), H300
Acute toxicity, Dermal (Category 4), H312
Reproductive toxicity (Category 1A), H360
Specific target organ toxicity - repeated exposure (Category 1), H372
Chronic aquatic toxicity (Category 3), H412
Label elements
PictogramGHS06 skull
skull
GHS08 silhouete
silhouete
GHS09 Aquatic-pollut-red
Aquatic-pollut-red
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram Signal word Danger
Hazard statement(s)
H300 Fatal if swallowed.
H312 Harmful in contact with skin. H360 May damage fertility or the unborn child.
H372 Causes damage to organs through prolonged or repeated exposure.
H412 Harmful to aquatic life with long lasting effects.
Precautionary statement(s)
P201 Obtain special instructions before use.
P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P301 + P330 + P331 + P310 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately
call a POISON CENTER/doctor.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
Supplemental Hazard
Statements
none
Restricted to professional users.
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Synonyms : Coumafene
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
Formula : C19H16O4
Molecular weight : 308.33 g/mol
CAS-No. : 81-81-2
EC-No. : 201-377-6
Index-No. : 607-056-00-0
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Warfarin
CAS-No.
EC-No.
Index-No.
81-81-2
201-377-6
607-056-00-0
Acute Tox. 1; Acute Tox. 4;
Repr. 1A; STOT RE 1; Aquatic
Chronic 3; H300, H312, H360,
H372, H412
<= 100 %
FormulaC19H15NaO4
Molecular Weight (g/mol)330.31
CAS-No.129-06-6
FIRST AID MEASURES4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician 4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Avoid exposure - obtain special
instructions before use.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Storage class (TRGS 510): Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
Colour: white
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing
point
Melting point/range: 162 - 164 °C - lit.
f) Initial boiling point and
boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower
flammability or
explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility insoluble
o) Partition coefficient: noctanol/
water
No data available
p) Auto-ignition
temperature
No data available q) Decomposition
temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available
STABILITY AND REACTIVITY10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
Strong oxidizing agents, Strong acids, Strong bases
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides
Other decomposition products - No data available
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 1.6 mg/kg(Warfarin)
LD50 Dermal - Rat - 1,400 mg/kg(Warfarin)
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and Taste):Eye:Chromodacryorrhea.
Behavioral:Muscle weakness. Kidney, Ureter, Bladder:Hematuria.
Skin corrosion/irritation
No data available(Warfarin)
Serious eye damage/eye irritation
No data available(Warfarin)
Respiratory or skin sensitisation
No data available(Warfarin)
Germ cell mutagenicity
No data available(Warfarin)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
May cause congenital malformation in the fetus.(Warfarin)
Known human reproductive toxicant(Warfarin)
Specific target organ toxicity - single exposure
No data available(Warfarin) Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available(Warfarin)
Additional Information
RTECS: GN4550000
Inhibition of blood coagulation., Abnormal clotting, bruising or bleeding.(Warfarin)
ECOLOGICAL INFORMATION12.1 Toxicity
Toxicity to fish LC50 - Oncorhynchus mykiss (rainbow trout) - > 16 mg/l - 96.0 h(Warfarin)
Toxicity to daphnia and
other aquatic
invertebrates
EC50 - Daphnia magna (Water flea) - > 17 mg/l - 48 h(Warfarin)
12.2 Persistence and degradability
Biodegradability Result: - Readily biodegradable
(OECD Test Guideline 301D)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available(Warfarin)
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects
Harmful to aquatic life with long lasting effects
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chem scrubber.
Contaminated packaging
Dispose of as unused product
TRANSPORT INFORMATION14.1 UN number
ADR/RID: 2811 IMDG: 2811 IATA: 2811
14.2 UN proper shipping name
ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (Warfarin)
IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Warfarin)
IATA: Toxic solid, organic, n.o.s. (Warfarin)
14.3 Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group
ADR/RID: I IMDG: I IATA: I 14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
REGULATORY INFORMATION15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!