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Trimethoprim

ISO 17034 Reference Material

Item number672980
CAS738-70-5
FormulaC14H18N4O3
Molecular weight290,32 g/mol
Quantity 1X250MG
storage conditions20 °C
CoA / MSDSRetrieve CoA
Retrieve MSDS
Trimethoprim

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Part of Product groups:
Product Variations:

Product

Catalog No./ CAS No.

Quantity

Price

13C3-Trimethoprim

13C3-Trimethoprim

690407
1189970-95-3

1X10MG

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13C3-Trimethoprim solution
Concentration: 100 µg/ml
Solvent: Acetonitrile

13C3-Trimethoprim solution

690443
1189970-95-3

1X1ML

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D9-Trimethoprim

D9-Trimethoprim

679828
1189460-62-5

1X10MG

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D9-Trimethoprim solution
Concentration: 100 µg/ml
Solvent: Methanol

D9-Trimethoprim solution

687614
1189460-62-5

1X1ML

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ISO 17034 Reference Material

Trimethoprim

Trimethoprim

672980
738-70-5

1X250MG

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Trimethoprim solution
Concentration: 100 µg/ml
Solvent: Methanol

Trimethoprim solution

679824
738-70-5

1X1ML

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ISO 17034 Certified Reference Material

Trimethoprim

Trimethoprim

691054
738-70-5

1X100MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 05.12.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Trimethoprim
Catalog No.:672980
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Label elements
Pictogram
2.2 Label elements
The product does not need to be labelled in accordance with EC directives or respective national laws.
2.3 Other hazards - none
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Synonyms : 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
Formula : C14H18N4O3
Molecular Weight : 290,32 g/mol
FormulaC14H18N4O3
Molecular Weight (g/mol)290.32
CAS-No.738-70-5
FIRST AID MEASURES4.1 Description of first aid measures
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
In case of skin contact
Wash off with soap and plenty of water.
In case of eye contact
Flush eyes with water as a precaution If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
4.2 Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
4.3 Indication of any immediate medical attention and special treatment needed
no data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx)
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
no data available
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing vapors, mist or gas.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Provide appropriate exhaust ventilation at places where dust is formed.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature: 2 - 8 °C
Product is sensitive to light and moisture.
7.3 Specific end use(s)
no data available
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
General industrial hygiene practice.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards
such as NIOSH (US) or EN 166(EU). Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands. Body Protection
Choose body protection in relation to its type, to the concentration and amount of dangerous
substances, and to the specific work-place., The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Respiratory protection is not required. Where protection from nuisance levels of dusts are desired,
use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN (EU).
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing
point
Melting point/range: 234 - 236 °C
f) Initial boiling point and
boiling range
no data available
g) Flash point no data available
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower
flammability or
explosive limits
no data available
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density no data available n) Water solubility no data available
o) Partition coefficient: noctanol/
water
no data available
p) Auto-ignition
temperature
no data available
q) Decomposition
temperature
no data available
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
9.2 Other safety information
no data available
STABILITY AND REACTIVITY10.1 Reactivity
no data available
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
no data available
10.4 Conditions to avoid
Avoid moisture.
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Other decomposition products - no data available
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - rat - > 5.300 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
Genotoxicity in vitro - Human - lymphocyte
Micronucleus test
Genotoxicity in vitro - Human - lymphocyte
Other mutation test systems
Genotoxicity in vitro - Human - lymphocyte
DNA inhibition
Genotoxicity in vitro - Human - lymphocyte
Sister chromatid exchange
Genotoxicity in vivo - rat - Unreported
sperm Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Reproductive toxicity - rat - Oral
Effects on Fertility: Post-implantation mortality (e.g., dead and/or resorbed implants per total number of
implants). Effects on Embryo or Fetus: Fetotoxicity (except death, e.g., stunted fetus).
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes May cause eye irritation.
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
Additional Information
RTECS: UV8225000
ECOLOGICAL INFORMATION12.1 Toxicity
no data available
12.2 Persistence and degradability
no data available
12.3 Bioaccumulative potential
no data available
12.4 Mobility in soil
no data available
12.5 Results of PBT and vPvB assessment
no data available
12.6 Other adverse effects
no data available
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.
TRANSPORT INFORMATION14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine Pollutant: no IATA: no
14.6 Special precautions for user
no data available
REGULATORY INFORMATIONThis safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
15.2 Chemical Safety Assessment
no data available
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!