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2-Methoxyethanol

Item number	679778
CAS	109-86-4
Formula	C3H8O2
Molecular weight	76,09 g/mol
Quantity	1X1ML
storage conditions	20 °C
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Product		Catalog No./ CAS No.	Quantity	Price
2-Methoxyethanol		679778 109-86-4	1X1ML	Please log in.
D3-2-Methoxyethanol		687154 97840-77-2	1X10MG	On request

Safety Data Sheet	according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 17.11.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:	2-Methoxyethanol
Catalog No.:	679778
Relevant identified uses of the substance or mixture	Identified: Laboratory chemical uses: R&D
Uses advised against:	HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com
Emergency telephone number	HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours.
HAZARDS IDENTIFICATION	2.1 Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) Flammable liquids (Category 3), H226 Acute toxicity, Oral (Category 4), H302 Acute toxicity, Inhalation (Category 4), H332 Acute toxicity, Dermal (Category 4), H312 Reproductive toxicity (Category 1B), H360 Specific target organ toxicity - single exposure (Category 1), Immune system, H370 Specific target organ toxicity - repeated exposure (Category 2), thymus, H373
Label elements
Pictogram	flamme flamme GHS07 exclam exclam GHS08 silhouete silhouete
	2.2 GHS Label elements, including precautionary Statements Signal word Danger Hazard statement(s) H226 Flammable liquid and vapour. H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled. H360 May damage fertility or the unborn child. H370 Causes damage to organs (Immune system). H373 May cause damage to organs (thymus) through prolonged or repeated exposure. Precautionary statement(s) P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking. P233 Keep container tightly closed. P240 Ground/bond container and receiving equipment. P241 Use explosion-proof electrical/ ventilating/ lighting equipment. P242 Use only non-sparking tools. P243 Take precautionary measures against static discharge. P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P307 + P311 IF exposed: Call a POISON CENTER or doctor/ physician. P363 Wash contaminated clothing before reuse. P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P403 + P235 Store in a well-ventilated place. Keep cool. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant. 2.3 Hazards not otherwise classified (HNOC) or not covered by GHS - none
COMPOSITION/INFORMATION ON INGREDIENTS	3.1 Substances Synonyms : Ethylene glycol monomethyl ether Methyl Cellosolve Methyl glycol Formula : C3H8O2 Molecular weight : 76.09 g/mol CAS-No. : 109-86-4 EC-No. : 203-713-7 Index-No. : 603-011-00-4 Component: 2-Methoxyethanol Classification: Flam. Liq. 3; Acute Tox. 4; Acute Tox. 3; Acute Tox. 4; Repr. 1B; STOT SE 1; STOT RE 2; H226, H302, H331, H312, H360, H370, H373 Concentration: <=100%
Formula	C3H8O2
Molecular Weight (g/mol)	76.09
CAS-No.	109-86-4
FIRST AID MEASURES	4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. Move out of dangerous area. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Flush eyes with water as a precaution. If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available
FIRE-FIGHTING MEASURES	5.1 Extinguishing media Suitable extinguishing media Dry powder Dry sand Unsuitable extinguishing media Do NOT use water jet. 5.2 Special hazards arising from the substance or mixture Carbon oxides 5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary. 5.4 Further information Use water spray to cool unopened containers.
ACCIDENTAL RELEASE MEASURES	6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13). 6.4 Reference to other sections For disposal see section 13.
HANDLING AND STORAGE	7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas. Storage class (TRGS 510): 3: Flammable liquids 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION	8.1 Control parameters Components with workplace control Parameters TWA: 1 ppm Europe. COMMISSION DIRECTIVE 2009/161/EU establishing a third list of indicative occupational exposure limit values in implementation of Council Directive 98/24/EC and amending Commission Directive 2000/39/EC Remarks: Remarks Identifies the possibility of significant uptake through the skin Indicative TWA: 1 ppm / 3 mg/m³ UK. EH40 WEL - Workplace Exposure Limits Can be absorbed through skin. The assigned substances are those for which there are concerns that dermal absorption will lead to systemic toxicity. Where no specific short-term exposure limit is listed, a figure three times the long-term exposure should be used 8.2 Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching gloves outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
PHYSICAL AND CHEMICAL PROPERTIES	9.1 Information on basic physical and chemical properties a) Appearance Form: clear, liquid Colour: colourless b) Odour ether-like c) Odour Threshold No data available d) pH 5.0 - 7.0 at 25 °C e) Melting point/freezing point Melting point/range: -85 °C - lit. f) Initial boiling Point and boiling range 124 - 125 °C - lit. g) Flash point 40 °C - closed cup h) Evaporation rate No data available i) Flammability (solid, gas) No data available j) Upper/lower flammability or explosive limits Upper explosion limit: 24.5 %(V) Lower explosion limit: 2.5 %(V) k) Vapour pressure 10 hPa at 20 °C l) Vapour density 2.63 - (Air = 1.0) m) Relative density 0.965 g/cm3 at 25 °C n) Water solubility soluble o) Partition coefficient: n-octanol/water log Pow: -0.8 p) Auto-ignition temperature No data available q) Decomposition temperature 204 - 232 °C - r) Viscosity 1.6 mm2/s at 20 °C - s) Explosive properties Not explosive t) Oxidizing properties No data available 9.2 Other safety information Relative vapour density 2.63 - (Air = 1.0)
STABILITY AND REACTIVITY	10.1 Reactivity Vapours may form explosive mixture with air. 10.2 Chemical stability Stable under recommended storage conditions. Contains the following stabiliser(s): 2,6-di-tert-Butyl-p-cresol (0.005 %) 10.3 Possibility of hazardous reactions No data available 10.4 Conditions to avoid Heat, flames and sparks. 10.5 Incompatible materials Aluminum, Magnesium, Alkalis, Strong oxidizing agents 10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5
TOXICOLOGICAL INFORMATION	11.1 Information on toxicological effects Acute toxicity LD50 Oral - Rat - male - 2,257 mg/kg (OECD Test Guideline 401) LC50 Inhalation - Rat - 4 h - 12.4 - 17.8 mg/l LD50 Dermal - Rabbit - 1,280 mg/kg LD50 Intraperitoneal - Rat - 2,500 mg/kg Skin corrosion/irritation Skin - Rabbit Result: No skin irritation (Directive 67/548/EEC, Annex V, B.4.) Serious eye damage/eye irritation Eyes - Rabbit Result: Mild eye irritation - 24 h (OECD Test Guideline 405) Respiratory or skin sensitisation Maximisation Test - Guinea pig Result: Does not cause skin sensitisation. Germ cell mutagenicity In vitro mammalian cell gene mutation test Chinese hamster ovary cells Result: negative OECD Test Guideline 475 Mouse - male Result: negative Carcinogenicity No data available IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity May cause congenital malformation in the fetus. Presumed human reproductive toxicant May cause reproductive disorders. Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure May cause damage to organs through prolonged or repeated exposure. - thymus Oral - Testes, thymus Aspiration hazard No data available Additional Information Repeated dose toxicity - Rat - male - Oral - No observed adverse effect level - < 71 mg/kg RTECS: KL5775000 Effects due to ingestion may include: Changes in the blood count, Headache, Central nervous system depression, Ingestion of large amounts may cause: Damage of the: Liver, Kidney, Central nervous system To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
ECOLOGICAL INFORMATION	12.1 Toxicity Toxicity to fish static test LC50 - Lepomis macrochirus (Bluegill) - 10,000 mg/l - 96 h (OECD Test Guideline 203) Toxicity to daphnia and other aquatic invertebrates semi-static test EC50 - Daphnia magna (Water flea) - 27,000 mg/l - 48 h Toxicity to algae static test EC50 - Pseudokirchneriella subcapitata - 25,500 mg/l - 72 h 12.2 Persistence and degradability Biodegradability aerobic - Exposure time 20 d Result: 88 % - Readily biodegradable. 12.3 Bioaccumulative potential No bioaccumulation is to be expected (log Pow <= 4). 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. 12.6 Other adverse effects No data available
DISPOSAL CONSIDERATIONS	13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself. Contaminated packaging Dispose of as unused product.
TRANSPORT INFORMATION	14.1 UN number ADR/RID: 1188 IMDG: 1188 IATA: 1188 14.2 UN proper shipping name ADR/RID: ETHYLENE GLYCOL MONOMETHYL ETHER IMDG: ETHYLENE GLYCOL MONOMETHYL ETHER IATA: Ethylene glycol monomethyl ether 14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3 14.4 Packaging group ADR/RID: III IMDG: III IATA: III 14.5 Environmental hazards ADR/RID: yes IMDG Marine pollutant: yes IATA: no 14.6 Special precautions for user No data available
REGULATORY INFORMATION	15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Authorisations and/or restrictions on use REACH - Candidate List of Substances of Very High Concern for Authorisation (Article 59). : 2-Methoxyethanol REACH - Restrictions on the manufacture, placing on the market and use of certain dangerous substances, preparations and articles (Annex XVII) : REACH - Restrictions on the manufacture, placing on the market and use of certain dangerous substances, preparations and articles (Annex XVII) : REACH - Restrictions on the manufacture, placing on the market and use of certain dangerous substances, preparations and articles (Annex XVII) : 2-Methoxyethanol 15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
OTHER INFORMATION	The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only!