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Dimethylsulfoxide

Item number677827
CAS67-68-5
FormulaC2H6OS
Molecular weight78,13 g/mol
Quantity 1X5ML
storage conditions20 °C
CoA / MSDSRetrieve CoA
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Dimethylsulfoxide

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Dimethylsulfoxide

Dimethylsulfoxide

677827
67-68-5

1X5ML

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 15.01.2025
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Dimethylsulfoxide
Catalog No.:677827
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
Label elements
Pictogram
2.2 Label elements
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Rapidly absorbed through skin.
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Synonyms : DMSO
Methyl sulfoxide
Formula : C2H6OS
Molecular weight : 78,13 g/mol
CAS-No. : 67-68-5
EC-No. : 200-664-3 Registration number : 01-2119431362-50-XXXX
No components need to be disclosed according to the applicable regulations.
FormulaC2H6OS
Molecular Weight (g/mol)78.13
CAS-No.67-68-5
FIRST AID MEASURES4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
For small (incipient) fires, use media such as "alcohol" foam, dry chemical, or carbon dioxide. For large
fires, apply water from as far as possible. Use very large quantities (flooding) of water applied as a mist or
spray; solid streams of water may be ineffective. Cool all affected containers with flooding quantities of
water.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Sulphur oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
Use water spray to cool unopened containers.
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Avoid breathing vapours, mist or gas. Remove all sources of ignition. Beware of vapours accumulating to
form explosive concentrations. Vapours can accumulate in low areas.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and
place in container for disposal according to local regulations (see section 13). Keep in suitable, closed
containers for disposal. 6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic
charge.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Store under inert gas. hygroscopic
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands. Body Protection
Impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid, clear
Colour: colourless
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing
point
Melting point/range: 16 - 19 °C
f) Initial boiling point and
boiling range
189 °C
g) Flash point 87 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower
flammability or
explosive limits
Upper explosion limit: 42 %(V)
Lower explosion limit: 3,5 %(V)
k) Vapour pressure 0,55 hPa at 20 °C
l) Vapour density 2,70 - (Air = 1.0)
m) Relative density 1,1 g/mL
n) Water solubility completely miscible
o) Partition coefficient: noctanol/
water
log Pow: -2,03
p) Auto-ignition
temperature
No data available
q) Decomposition
temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative vapour density 2,70 - (Air = 1.0)
STABILITY AND REACTIVITY10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available 10.4 Conditions to avoid
Heat, flames and sparks.
10.5 Incompatible materials
Acid chlorides, Phosphorus halides, Strong acids, Strong oxidizing agents, Strong reducing agents
10.6 Hazardous decomposition products
Other decomposition products - No data available
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 14.500 mg/kg
LC50 Inhalation - Rat - 4 h - 40250 ppm
LD50 Dermal - Rabbit - > 5.000 mg/kg
Skin corrosion/irritation
Mild skin irritation
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitisation
No data available
Germ cell mutagenicity
Mouse
lymphocyte
Cytogenetic analysis
Mouse
lymphocyte
Mutation in mammalian somatic cells.
Rat
Cytogenetic analysis
Mouse
DNA damage
Carcinogenicity
Carcinogenicity - Rat - Oral
Tumorigenic:Equivocal tumorigenic agent by RTECS criteria. Skin and Appendages: Other: Tumors.
Carcinogenicity - Mouse - Oral
Tumorigenic:Equivocal tumorigenic agent by RTECS criteria. Leukaemia Skin and Appendages: Other:
Tumors.
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity Reproductive toxicity - Rat - Intraperitoneal
Effects on Fertility: Abortion.
Reproductive toxicity - Rat - Intraperitoneal
Effects on Fertility: Post-implantation mortality (e.g., dead and/or resorbed implants per total number of
implants).
Reproductive toxicity - Rat - Subcutaneous Effects on Fertility: Post-implantation mortality (e.g., dead and/or resorbed implants per total number of
implants). Effects on Fertility: Litter size (e.g.; # fetuses per litter; measured before birth).
Reproductive toxicity - Mouse - Oral
Effects on Fertility: Pre-implantation mortality (e.g., reduction in number of implants per female; total
number of implants per corpora lutea). Effects on Embryo or Fetus: Fetotoxicity (except death, e.g.,
stunted fetus). Specific Developmental Abnormalities: Musculoskeletal system.
Developmental Toxicity - Mouse - Intraperitoneal
Effects on Embryo or Fetus: Fetotoxicity (except death, e.g., stunted fetus). Specific Developmental
Abnormalities: Musculoskeletal system.
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
RTECS: PV6210000
Exposure to large amounts can cause:, redness of skin, Itching, burning, sedation, Headache, Nausea,
Dizziness
ECOLOGICAL INFORMATION12.1 Toxicity
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 34.000 mg/l - 96 h
LC50 - Oncorhynchus mykiss (rainbow trout) - 35.000 mg/l - 96 h
Toxicity to daphnia and
other aquatic
invertebrates
EC50 - Daphnia magna (Water flea) - 24.600 mg/l - 48 h
(OECD Test Guideline 202)
Toxicity to algae EC50 - Pseudokirchneriella subcapitata (green algae) - 17.000 mg/l - 72 h
(OECD Test Guideline 201)
12.2 Persistence and degradability
Biodegradability Result: 31 % - According to the results of tests of biodegradability this product
is not readily biodegradable.
(OECD Test Guideline 301D)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects
No data available
Stability in water - 0,12 - 1,2 h at 30 °C
Remarks: Hydrolyses readily.
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
This combustible material may be burned in a chemical incinerator equipped with an afterburner and
scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed
professional waste disposal service to dispose of this material.
Contaminated packaging
Dispose of as unused product.
TRANSPORT INFORMATION14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
REGULATORY INFORMATION15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
International Chemical Weapons Convention (CWC)
Schedules of Toxic Chemicals and Precursors
: Neither banned nor restricted
Restrictions on the marketing and use of certain
dangerous substances and preparations
: Neither banned nor restricted
Regulation (EC) No 649/2012 of the European
Parliament and the Council concerning the export and
import of dangerous chemicals
: Neither banned nor restricted
REACH - Candidate List of Substances of Very High
Concern for Authorisation (Article 59).
: This product does not contain
substances of very high concern
(Regulation (EC) No
1907/2006 (REACH), Article 57).
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!