Products

1,4-Androstadiene-3,17-dione

Item number	679912
CAS	897-06-3
Formula	C19H24O2
Molecular weight	284,39 g/mol
Quantity	1X100MG
storage conditions	20 °C
CoA / MSDS	Retrieve CoA Retrieve MSDS

Price

Please log in.

Product Variations:

Product		Catalog No./ CAS No.	Quantity	Price
1,4-Androstadiene-3,17-dione		679912 897-06-3	1X100MG	Please log in.

Safety Data Sheet	according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 18.10.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:	1,4-Androstadiene-3,17-dione
Catalog No.:	679912
Relevant identified uses of the substance or mixture	Identified: Laboratory chemical uses: R&D
Uses advised against:	HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com
Emergency telephone number	HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours.
HAZARDS IDENTIFICATION	Classification according to Regulation (EC) No 1272/2008 Carcinogenicity (Category 2), H351 Reproductive toxicity (Category 1B), H360FD Effects on or via lactation, H362 Long-term (chronic) aquatic hazard (Category 2), H411 For the full text of the H-Statements mentioned in this Section, see Section 16.
Label elements
Pictogram	GHS08 silhouete silhouete GHS09 Aquatic-pollut-red Aquatic-pollut-red
	Labelling according Regulation (EC) No 1272/2008 Pictogram Signal word Danger Hazard statement(s) H351 Suspected of causing cancer. H360FD May damage fertility. May damage the unborn child. H362 May cause harm to breast-fed children. H411 Toxic to aquatic life with long lasting effects. Precautionary statement(s) P201 Obtain special instructions before use. P260 Do not breathe dusts or mists. P263 Avoid contact during pregnancy and while nursing. P273 Avoid release to the environment. P308 + P313 IF exposed or concerned: Get medical advice/ attention. Supplemental Hazard Statements none Reduced Labeling (<= 125 ml) Pictogram Signal word Danger Hazard statement(s) H351 Suspected of causing cancer. H362 May cause harm to breast-fed children. H360FD May damage fertility. May damage the unborn child. Precautionary statement(s) P201 Obtain special instructions before use. P308 + P313 IF exposed or concerned: Get medical advice/ attention. Supplemental Hazard Statements none 2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
COMPOSITION/INFORMATION ON INGREDIENTS	Substances Synonyms : Androstadienedione 1-Dehydroandrostenedione Formula : C19H24O2 Molecular weight : 284,39 g/mol CAS-No. : 897-06-3 EC-No. : 212-977-2 Component Androsta-1,4-diene-3,17-dione CAS-No. : 897-06-3 EC-No. : 212-977-2 Classification Carc. 2; Repr. 1B; Lact. ; Aquatic Chronic 2; H351,H360FD, H362, H411 Concentration <= 100 % For the full text of the H-Statements mentioned in this Section, see Section 16.
Formula	C19H24O2
Molecular Weight (g/mol)	284.39
CAS-No.	897-06-3
FIRST AID MEASURES	4.1 Description of first-aid measures General advice Consult a physician. Show this material safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Flush eyes with water as a precaution. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available
FIRE-FIGHTING MEASURES	5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. 5.2 Special hazards arising from the substance or mixture Carbon oxides 5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary. 5.4 Further information No data available
ACCIDENTAL RELEASE MEASURES	6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. 6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. 6.4 Reference to other sections For disposal see section 13.
HANDLING AND STORAGE	7.1 Precautions for safe handling Advice on safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Advice on safe handling Avoid exposure - obtain special instructions before use. Advice on protection against fire and explosion Provide appropriate exhaust ventilation at places where dust is formed. Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Storage conditions Keep container tightly closed in a dry and well-ventilated place. Store in cool place. Storage class Storage class (TRGS 510): 6.1C: Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION	8.1 Control parameters Ingredients with workplace control parameters 8.2 Exposure controls Personal protective equipment Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching gloves outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a fullface particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
PHYSICAL AND CHEMICAL PROPERTIES	9.1 Information on basic physical and chemical properties a) Physical state solid b) Color No data available c) Odor No data available d) Melting point/freezing point Melting point/range: 138 - 139 °C 129,2 °C e) Initial boiling point and boiling range 296,1 °C f) Flammability (solid, gas) No data available g) Upper/lower flammability or explosive limits No data available h) Flash point No data available i) Autoignition temperature No data available j) Decomposition temperature No data available k) pH No data available l) Viscosity Viscosity, kinematic: No data available Viscosity, dynamic: No data available m) Water solubility 0,43 g/l at 20 °C - OECD Test Guideline 105 n) Partition coefficient: n-octanol/water log Pow: 2,2 at 25 °C - OECD Test Guideline 117 - Bioaccumulation is not expected. o) Vapor pressure < 1 hPa at 20 °C - OECD Test Guideline 104 p) Density 1,183 g/cm3 at 20 °C - OECD Test Guideline 109 Relative density No data available q) Relative vapor density No data available r) Particle characteristics No data available s) Explosive properties No data available t) Oxidizing properties none 9.2 Other safety information No data available
STABILITY AND REACTIVITY	10.1 Reactivity No data available 10.2 Chemical stability Stable under recommended storage conditions. 10.3 Possibility of hazardous reactions No data available 10.4 Conditions to avoid No data available 10.5 Incompatible materials Strong acids, Strong bases 10.6 Hazardous decomposition products In the event of fire: see section 5
TOXICOLOGICAL INFORMATION	11.1 Information on toxicological effects Acute toxicity LD50 Oral - Rat - female - 2.000 mg/kg (OECD Test Guideline 423) Inhalation: No data available LD50 Dermal - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 402) Skin corrosion/irritation Skin - Rat Result: No skin irritation (OECD Test Guideline 404) Serious eye damage/eye irritation Eyes - Rabbit Result: No eye irritation (OECD Test Guideline 405) Respiratory or skin sensitization No data available Germ cell mutagenicity Test Type: Ames test Test system: Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative Test Type: Micronucleus test Species: Rat Cell type: Bone marrow Application Route: Oral Method: OECD Test Guideline 474 Result: negative Carcinogenicity Suspected of causing cancer. Reproductive toxicity May damage fertility. May damage the unborn child. Studies indicating a hazard to babies during the lactation period Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available 11.2 Additional Information RTECS: BV7988000 Some steroids show carcinogenic and teratogenic activity.
ECOLOGICAL INFORMATION	12.1 Toxicity Toxicity to fish semi-static test LC50 - Danio rerio (zebra fish) - 23,3 mg/l - 96 h (OECD Test Guideline 203) Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - 49,8 mg/l - 48 h (OECD Test Guideline 202) Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 1,3 mg/l - 72 h (OECD Test Guideline 201) static test NOEC - Desmodesmus subspicatus (green algae) - 0,1 mg/l - 72 h (OECD Test Guideline 201) Toxicity to bacteria static test EC10 - Pseudomonas putida - > 382,6 mg/l - 16 h (DIN 38421 TEIL 8) 12.2 Persistence and degradability Biodegradability aerobic - Exposure time 28 d Result: 93 % - Readily biodegradable. (OECD Test Guideline 301E) 12.3 Bioaccumulative potential No data available 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. 12.6 Endocrine disrupting properties No data available 12.7 Other adverse effects Toxic to aquatic life with long lasting effects. No data available Stability in water DT50 - > 1 yr at 25 °C pH 7 - 0 % (Directive 67/548/EEC, Annex V, C.10.)
DISPOSAL CONSIDERATIONS	13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself. Contaminated packaging Dispose of as unused product.
TRANSPORT INFORMATION	14.1 UN number ADR/RID: 3077 IMDG: 3077 IATA: 3077 14.2 UN proper shipping name ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Androsta-1,4- diene-3,17-dione) IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Androsta-1,4- diene-3,17-dione) IATA: Environmentally hazardous substance, solid, n.o.s. (Androsta-1,4-diene-3,17- dione) 14.3 Transport hazard class(es) ADR/RID: 9 IMDG: 9 IATA: 9 14.4 Packaging group ADR/RID: III IMDG: III IATA: III 14.5 Environmental hazards ADR/RID: yes IMDG Marine pollutant: yes IATA: yes 14.6 Special precautions for user Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
REGULATORY INFORMATION	15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006. National legislation Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of major-accident hazards involving dangerous substances. : ENVIRONMENTAL HAZARDS 15.2 Chemical Safety Assessment For this product a chemical safety assessment was not carried out
OTHER INFORMATION	The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only!