Products

2-Aminopyridine

Item number	682362
CAS	504-29-0
Formula	C5H6N2
Molecular weight	94,11 g/mol
Quantity	1X500MG
storage conditions	20 °C
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Aminopyridine

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Product	Catalog No./ CAS No.	Quantity	Price
2-Aminopyridine	682362 504-29-0	1X500MG	Please log in.
3-Aminopyridine	682994 462-08-8	1X500MG	On request
4-Aminopyridine	682517 504-24-5	1X1000MG	Please log in.

Safety Data Sheet	according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 25.11.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:	2-Aminopyridine
Catalog No.:	682362
Relevant identified uses of the substance or mixture	Identified: Laboratory chemical uses: R&D
Uses advised against:	HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com
Emergency telephone number	HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours.
HAZARDS IDENTIFICATION	2.1. Classification of the substance or mixture Regulation (EC) No 1272/2008 Acute toxicity - Oral Category 3 - (H301) Acute toxicity - Dermal Category 3 - (H311) Acute toxicity - Inhalation (Dusts/Mists) Category 3 - (H331) Skin corrosion/irritation Category 1 Sub-category B - (H314) Serious eye damage/eye irritation Category 1 - (H318) Chronic aquatic toxicity Category 3 - (H412)
Label elements
Pictogram	GHS05 acid acid GHS06 skull skull
	2.2. Label elements 207-988-4 Contains 2-Pyridylamine Signal word Danger Hazard statements H301 - Toxic if swallowed H311 - Toxic in contact with skin H314 - Causes severe skin burns and eye damage H331 - Toxic if inhaled H412 - Harmful to aquatic life with long lasting effects Precautionary Statements - EU (§28, 1272/2008) P260 - Do not breathe dust/fume/gas/mist/vapours/spray P280 - Wear protective gloves/protective clothing and eye/face protection P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower] P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor P331 - Do NOT induce vomiting P403 + P233 - Store in a well-ventilated place. Keep container tightly closed 2.3. Other hazards Harmful to aquatic life. This substance does not meet the PBT/vPvB criteria of REACH, annex XIII. Chemical name: 2-Pyridylamine EU - REACH (1907/2006) - Article 59(1) - Candidate List of Substances of Very High Concern (SVHC) for Authorisation: - EU - REACH (1907/2006) - Endocrine Disruptor Assessment List of Substances: -
COMPOSITION/INFORMATION ON INGREDIENTS	3.1 Substances Chemical name: 2-Pyridylamine 504-29-0 Weight-%: 100 REACH registration number: - EC No: 207-988-4 Classification according to Regulation (EC) No. 1272/2008 [CLP]: Acute Tox. 3 (H301) Acute Tox. 3 (H311) Acute Tox. 3 (H331) Skin Corr. 1B (H314) Eye Dam. 1 (H318) Aquatic Chronic 3 (H412) Specific concentration limit (SCL) M-Factor M-Factor (long-term) Acute Toxicity Estimate If LD50/LC50 data is not available or does not correspond to the classification category, then the appropriate conversion value from CLP Annex I, Table 3.1.2, is used to calculate the acute toxicity estimate (ATEmix) for classifying a mixture based on its components Chemical name: 2-Pyridylamine 504-29-0 Oral LD50 mg/kg: 200 Dermal LD50 mg/kg: 1000 Inhalation LC50 - 4 hour - dust/mist - mg/L: No data available Inhalation LC50 - 4 hour - vapour - mg/L: No data available nhalation LC50 - 4 hour - gas - ppm: No data available This product does not contain candidate substances of very high concern at a concentration >=0.1% (Regulation (EC) No. 1907/2006 (REACH), Article 59)
Formula	C5H6N2
Molecular Weight (g/mol)	94.11
CAS-No.	504-29-0
FIRST AID MEASURES	4.1. Description of first aid measures General advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required. Inhalation Remove to fresh air. If breathing has stopped, give artificial respiration. Get medical attention immediately. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. If breathing is difficult, (trained personnel should) give oxygen. Delayed pulmonary edema may occur. Get immediate medical advice/attention. Do not breathe dust. Eye contact Get immediate medical advice/attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Keep eye wide open while rinsing. Do not rub affected area. Remove contact lenses, if present and easy to do. Continue rinsing. Skin contact Get immediate medical advice/attention. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Ingestion Do NOT induce vomiting. Rinse mouth. Never give anything by mouth to an unconscious person. Get immediate medical advice/attention. Self-protection of the first aider Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination. Avoid contact with skin, eyes or clothing. Do not breathe dust. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Use personal protective equipment as required. See section 8 for more information. 4.2. Most important symptoms and effects, both acute and delayed Symptoms Burning sensation. Coughing and/ or wheezing. Difficulty in breathing. 4.3. Indication of any immediate medical attention and special treatment needed Note to doctors Product is a corrosive material. Use of gastric lavage or emesis is contra-indicated. Possible perforation of stomach or esophagus should be investigated. Do not give chemical antidotes. Asphyxia from glottal edema may occur. Marked decrease in blood pressure may occur with moist rales, frothy sputum, and high pulse pressure.
FIRE-FIGHTING MEASURES	5.1. Extinguishing media Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Large Fire CAUTION: Use of water spray when fighting fire may be inefficient. Unsuitable extinguishing media Do not scatter spilled material with high pressure water streams. 5.2. Special hazards arising from the substance or mixture Specific hazards arising from the chemical The product causes burns of eyes, skin and mucous membranes. Thermal decomposition can lead to release of irritating gases and vapours. 5.3. Advice for firefighters Special protective equipment and precautions for fire-fighters Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear. Use personal protection equipment.
ACCIDENTAL RELEASE MEASURES	6.1. Personal precautions, protective equipment and emergency procedures Personal precautions Avoid contact with skin, eyes or clothing. Ensure adequate ventilation. Use personal protective equipment as required. Evacuate personnel to safe areas. Attention! Corrosive material. Keep people away from and upwind of spill/leak. Avoid generation of dust. Do not breathe dust. Other information Refer to protective measures listed in Sections 7 and 8. For emergency responders Use personal protection recommended in Section 8. 6.2. Environmental precautions Environmental precautions Prevent further leakage or spillage if safe to do so. Should not be released into the environment. Do not allow to enter into soil/subsoil. Prevent product from entering drains. 6.3. Methods and material for containment and cleaning up Methods for containment Prevent further leakage or spillage if safe to do so. Methods for cleaning up Take up mechanically, placing in appropriate containers for disposal. Prevention of secondary hazards Clean contaminated objects and areas thoroughly observing environmental regulations. 6.4. Reference to other sections Reference to other sections See section 8 for more information. See section 13 for more information.
HANDLING AND STORAGE	7.1. Precautions for safe handling Advice on safe handling Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin, eyes or clothing. Take off contaminated clothing and wash it before reuse. In case of insufficient ventilation, wear suitable respiratory equipment. Handle product only in closed system or provide appropriate exhaust ventilation. Do not eat, drink or smoke when using this product. Do not breathe dust. Avoid generation of dust. General hygiene considerations Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Regular cleaning of equipment, work area and clothing is recommended. Wash hands before breaks and immediately after handling the product. Contaminated work clothing should not be allowed out of the workplace. Do not breathe dust. Take off contaminated clothing and wash it before reuse. 7.2. Conditions for safe storage, including any incompatibilities Storage Conditions Please refer to the manufacturers certificate for specific storage and transport temperature conditions. Store only in the original receptacle unless other advice is given on the CoA. Keep containers tightly closed in a dry, cool and well-ventilated place. Keep out of the reach of children. Store locked up. Protect from moisture. Store away from other materials. 7.3. Specific end use(s) Risk Management Methods (RMM) The information required is contained in this Safety Data Sheet.
EXPOSURE CONTROLS/PERSONAL PROTECTION	8.1. Control parameters Exposure Limits Chemical name: 2-Pyridylamine 504-29-0 European Union: - Austria: TWA: 0.5 ppm TWA: 2 mg/m3 Belgium: TWA: 0.5 ppm TWA: 1.9 mg/m3 Bulgaria: - Croatia: TWA: 0.5 ppm TWA: 2 mg/m3 STEL: 2 ppm STEL: 8 mg/m3 STEL: 7.8 mg/m3 Cyprus: - Czech Republic: TWA: 2 mg/m3 Ceiling: 4 mg/m3 * Denmark: TWA: 0.5 ppm TWA: 2 mg/m3 Estonia: - Finland: TWA: 0.5 ppm TWA: 2 mg/m3 STEL: 1.5 ppm STEL: 5.9 mg/m3 France: TWA: 0.5 ppm TWA: 2 mg/m3 Germany: - Germany MAK: - Greece: TWA: 0.5 ppm TWA: 2 mg/m3 STEL: 2 ppm STEL: 8 mg/m3 Hungary: - Ireland: TWA: 0.5 ppm TWA: 2 mg/m3 STEL: 1.5 ppm STEL: 6 mg/m3 Italy: - Italy REL: TWA: 0.5 ppm TWA: 1.9 mg/m3 Latvia: - Lithuania: - Luxembourg: - Malta: - Netherlands: - Norway: TWA: 0.5 ppm TWA: 2 mg/m3 STEL: 1.5 ppm STEL: 4 mg/m3 Poland: TWA: 2 mg/m3 * Portugal: TWA: 0.5 ppm Romania: - Slovakia: TWA: 0.5 ppm TWA: 2 mg/m3 Slovenia: - Spain: TWA: 0.5 ppm TWA: 1.9 mg/m3 Sweden: - Switzerland: TWA: 0.5 ppm TWA: 2 mg/m3 United Kingdom: TWA: 0.5 ppm TWA: 2 mg/m3 STEL: 2 ppm STEL: 7.8 mg/m3 Biological occupational exposure limits This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies Derived No Effect Level (DNEL) No information available. Predicted No Effect Concentration (PNEC) No information available. 8.2. Exposure controls Personal protective equipment Eye/face protection Avoid contact with eyes. Wear safety glasses with side shields (or goggles). Tight sealing safety goggles. Face protection shield. Hand protection Wear suitable gloves. Impervious gloves. The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374. Wear protective butyl rubber gloves. Polyvinyl chloride (PVC). Skin and body protection Wear suitable protective clothing. Long sleeved clothing. Chemical resistant apron. Respiratory protection No protective equipment is needed under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required. General hygiene considerations Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Regular cleaning of equipment, work area and clothing is recommended. Wash hands before breaks and immediately after handling the product. Contaminated work clothing should not be allowed out of the workplace. Do not breathe dust. Take off contaminated clothing and wash it before reuse. Environmental exposure controls Do not allow into any sewer, on the ground or into any body of water.
PHYSICAL AND CHEMICAL PROPERTIES	9.1. Information on basic physical and chemical properties Physical state Solid Appearance Solid Colour light yellow Odour Characteristic. pyridine-like Odour threshold No information available Property Values Remarks • Method Melting point / freezing point 56 - 59 °C None known Initial boiling point and boiling range 204 °C None known Flammability No data available None known Flammability Limit in Air None known Upper flammability or explosive limits No data available Lower flammability or explosive limits No data available Flash point No data available None known Autoignition temperature > 630 °C None known Decomposition temperature None known pH No data available None known pH (as aqueous solution) No data available No information available Kinematic viscosity No data available None known Dynamic viscosity No data available None known Water solubility Soluble in water 890 g/L @ 21 °C Solubility(ies) Ether, Alcohols, Benzene, Acetone Partition coefficient 0.49 None known Vapour pressure 0.8 mmHg @ 25 °C None known Relative density 1.065 None known Bulk density No data available Liquid Density No data available Relative vapour density 3.25 None known Particle characteristics Particle Size No information available Particle Size Distribution No information available 9.2. Other information Molecular weight 94.12 Molecular formula C5 H6 N2 9.2.1. Information with regards to physical hazard classes Not applicable 9.2.2. Other safety characteristics No information available
STABILITY AND REACTIVITY	10.1. Reactivity Reactivity No information available. 10.2. Chemical stability Stability Stable under normal conditions. Explosion data Sensitivity to mechanical impact None. Sensitivity to static discharge None. 10.3. Possibility of hazardous reactions Possibility of hazardous reactions None under normal processing. 10.4. Conditions to avoid Conditions to avoid Exposure to air or moisture over prolonged periods. Excessive heat. 10.5. Incompatible materials Incompatible materials Acids. Bases. Oxidising agent. Hazardous decomposition products None known based on information supplied.
TOXICOLOGICAL INFORMATION	11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008 Information on likely routes of exposure Product Information Inhalation Specific test data for the substance or mixture is not available. Corrosive by inhalation. (based on components). Inhalation of corrosive fumes/gases may cause coughing, choking, headache, dizziness, and weakness for several hours. Pulmonary edema may occur with tightness in the chest, shortness of breath, bluish skin, decreased blood pressure, and increased heart rate. Inhaled corrosive substances can lead to a toxic edema of the lungs. Pulmonary edema can be fatal. Toxic by inhalation. Eye contact Specific test data for the substance or mixture is not available. Causes serious eye damage. (based on components). Corrosive to the eyes and may cause severe damage including blindness. May cause irreversible damage to eyes. Skin contact Specific test data for the substance or mixture is not available. Corrosive. (based on components). Causes burns. Toxic in contact with skin. Ingestion Specific test data for the substance or mixture is not available. Causes burns. (based on components). Ingestion causes burns of the upper digestive and respiratory tracts. May cause severe burning pain in the mouth and stomach with vomiting and diarrhea of dark blood. Blood pressure may decrease. Brownish or yellowish stains may be seen around the mouth. Swelling of the throat may cause shortness of breath and choking. May cause lung damage if swallowed. May be fatal if swallowed and enters airways. Symptoms related to the physical, chemical and toxicological characteristics Symptoms Redness. Burning. May cause blindness. Coughing and/ or wheezing. Difficulty in breathing. Numerical measures of toxicity Acute toxicity Component Information Chemical name: 2-Pyridylamine Oral LD50: = 200 mg/kg ( Rat ) Dermal LD50: = 500 mg/kg ( Guinea Pig ) > 1000 mg/kg ( Rabbit ) Inhalation LC50: Delayed and immediate effects as well as chronic effects from short and long-term exposure Skin corrosion/irritation Classification based on data available for ingredients. Causes severe skin burns and eye damage. Serious eye damage/eye irritation Classification based on data available for ingredients. Causes serious eye damage. Causes burns. Respiratory or skin sensitisation No information available Germ cell mutagenicity No information available. Carcinogenicity No information available. Reproductive toxicity No information available. STOT - single exposure No information available. STOT - repeated exposure No information available. Aspiration hazard No information available. 11.2. Information on other hazards 11.2.1. Endocrine disrupting properties Endocrine disrupting properties No information available. 11.2.2. Other information Other adverse effects No information available.
ECOLOGICAL INFORMATION	12.1. Toxicity Ecotoxicity Harmful to aquatic life with long lasting effects. Chemical name: 2-Pyridylamine Algae/aquatic plants: - Fish: LC50: = 11 mg/l (96h, Oryzias latipes) Toxicity to microorganisms: - Crustacea: EC50: =35 mg/L (48h, Daphnia magna (Water flea)) 12.2. Persistence and degradability Persistence and degradability No information available. 12.3. Bioaccumulative potential Bioaccumulation There is no data for this product. Component Information Chemical name: 2-Pyridylamine Partition coefficient: 0.49 12.4. Mobility in soil Mobility in soil No information available. 12.5. Results of PBT and vPvB assessment PBT and vPvB assessment This substance is not considered to be persistent, bioaccumulating nor toxic (PBT). This substance is not considered to be very persistent nor very bioaccumulating (vPvB). Chemical name: 2-Pyridylamine PBT and vPvB assessment: PBT assessment does not apply 12.6. Endocrine disrupting properties Endocrine disrupting properties No information available. 12.7. Other adverse effects No information available.
DISPOSAL CONSIDERATIONS	13.1. Waste treatment methods Waste from residues/unused products Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation. Contaminated packaging Do not reuse empty containers.
TRANSPORT INFORMATION	IATA 14.1 UN number or ID number UN2671 14.2 UN proper shipping name Aminopyridines 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2671, Aminopyridines, 6.1, II 14.5 Environmental hazards Not applicable 14.6 Special precautions for user Special Provisions None ERG Code 6L IMDG 14.1 UN number or ID number UN2671 14.2 UN proper shipping name Aminopyridines (o-, m-, p-) 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2671, Aminopyridines (o-, m-, p-), 6.1, II 14.5 Marine pollutant NP 14.6 Special precautions for user Special Provisions None EmS-No F-A, S-A No information available 14.7 Maritime transport in bulk according to IMO instruments No information available RID 14.1 UN number or ID number UN2671 14.2 UN proper shipping name Aminopyridines 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2671, Aminopyridines, 6.1, II 14.5 Environmental hazards Not applicable 14.6 Special precautions for user Special Provisions None Classification code T2 ADR 14.1 UN number or ID number UN2671 14.2 UN proper shipping name Aminopyridines 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2671, Aminopyridines, 6.1, II, (D/E) 14.5 Environmental hazards Not applicable 14.6 Special precautions for user Special Provisions None Classification code T2 Tunnel restriction code (D/E)
REGULATORY INFORMATION	15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture National regulations Germany Water hazard class (WGK) obviously hazardous to water (WGK 2) Poland SDS created according to the following Polish regulation: Act of February 25, 2011 on chemical substances and their mixtures (Journal of Laws of 2018, item 143, as amended). Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), establishing the European Chemicals Agency (EC) as amended. Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labeling and packaging of substances and mixtures, as amended. Regulation of the Minister of Health of 10 August 2012 on the criteria and method of classifying chemical substances and their mixtures (Journal of Laws of 2012, item 1018). Regulation of the Minister of Health of 20 April 2012 on labeling packaging of hazardous substances and mixtures and some mixtures (Journal of Laws of 2012, item 445). Regulation of the Minister of Family, Labor and Social Policy of 12 June 2018 on the maximum allowable concentrations and intensities of factors harmful to health in the work environment (Journal of Laws of 2018, item 1286). Announcement of the Minister of Economy, Labor and Social Policy of August 28, 2003 on the publication of the unified text of the Ordinance of the Minister of Labor and Social Policy on general health and safety at work regulations (Journal of Laws of 2003, No. 169, item 1650) . Regulation of the Minister of Health of 30 December 2004 on occupational safety and health related to the presence of chemical agents in the workplace (Journal of Laws of 2005, No. 11, item 86). Act of December 14, 2012 on waste (Journal of Laws of 2013, item 21) Regulation of the Minister of Health of December 30, 2004 on occupational health and safety related to the presence of chemical agents in the workplace (Journal U. of 2005, No. 11, item 86). Waste Act of December 14, 2012 (Journal of Laws of 2013, item 21). Act of 13 June 2013 on the management of packaging and packaging waste, Journal of Laws 2013, item 888). Government statement of September 24, 2002 - European Agreement on the International Carriage of Dangerous Goods by Road (ADR) (Journal of Laws No. 194, item 1629 and Journal of Laws of 2003, No. 207, item 2013 and 2014). European Union Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Authorisations and/or restrictions on use: This product does not contain substances subject to authorisation (Regulation (EC) No. 1907/2006 (REACH), Annex XIV) This product does not contain substances subject to restriction (Regulation (EC) No. 1907/2006 (REACH), Annex XVII) DIRECTIVE (EU) 2021/1187 on the marketing and use of explosives precursors Not applicable Persistent Organic Pollutants Not applicable Dangerous substance category per Seveso Directive (2012/18/EU) H2 - ACUTE TOXIC Ozone-depleting substances (ODS) regulation (EC) 1005/2009 Not applicable International Inventories TSCA Contact supplier for inventory compliance status DSL/NDSL Contact supplier for inventory compliance status EINECS/ELINCS Contact supplier for inventory compliance status ENCS Contact supplier for inventory compliance status IECSC Contact supplier for inventory compliance status KECL Contact supplier for inventory compliance status PICCS Contact supplier for inventory compliance status AIIC Contact supplier for inventory compliance status Legend: TSCA - United States Toxic Substances Control Act Section 8(b) Inventory DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances ENCS - Japan Existing and New Chemical Substances IECSC - China Inventory of Existing Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances PICCS - Philippines Inventory of Chemicals and Chemical Substances AICS - Australian Inventory of Chemical Substances 15.2. Chemical safety assessment Chemical Safety Report A Chemical Safety Assessment has been carried out for this substance
OTHER INFORMATION	The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only!