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Flunisolide

Item number689948
CAS3385-03-3
FormulaC24H31FO6
Molecular weight434,50 g/mol
Quantity 1X50MG
storage conditions20 °C
CoA / MSDSRetrieve CoA
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Flunisolide

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Flunisolide

Flunisolide

689948
3385-03-3

1X50MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 14.11.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Flunisolide
Catalog No.:689948
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 1), H300 Classification according to EU Directives 67/548/EEC or 1999/45/EC
T+ Very toxic R28
Label elements
PictogramGHS06 skull
skull
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram Signal word Danger
Hazard statement(s)
H300 Fatal if swallowed.
Precautionary statement(s)
P264 Wash hands thoroughly after handling.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
Supplemental Hazard
Statements
none
2.3 Other hazards - none
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Synonyms : 6-Fluoro-11,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 16,17-acetonide
Formula : C24H31FO6
Molecular weight : 434,50 g/mol
CAS-No. : 3385-03-3
EC-No. : 222-193-2
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Flunisolide
CAS-No.
EC-No.
3385-03-3
222-193-2
Acute Tox. 1; H300 <= 100 %
Hazardous ingredients according to Directive 1999/45/EC
Component Classification Concentration
Flunisolide
CAS-No.
EC-No.
3385-03-3
222-193-2
T+, R28 <= 100 %
FormulaC24H31FO6
Molecular Weight (g/mol)434.50
CAS-No.3385-03-3
FIRST AID MEASURES4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide 5.2 Special hazards arising from the substance or mixture
Carbon oxides, Hydrogen fluoride
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
protection.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
the product.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry Hands Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing
point
No data available
f) Initial boiling point and
boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower
flammability or
explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility No data available
o) Partition coefficient: n- No data available octanol/water
p) Auto-ignition
temperature
No data available
q) Decomposition
temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available
STABILITY AND REACTIVITY10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
Other decomposition products - No data available
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Mouse - > 0,5 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity). Blood:Aplastic anemia. Nutritional and
Gross Metabolic:Weight loss or decreased weight gain.
TDLo Oral - Rat - 0,630 mg/kg
Remarks: Paternal Effects: Testes, epididymis, sperm duct.
TDLo Oral - Rat - 1,05 mg/kg
TDLo Oral - Rat - 1,1 mg/kg
TDLo Oral - Rat - 0,550 mg/kg
TDLo Oral - Rat - 0,026 mg/kg
LD50 Intravenous - Rat - > 51 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity). Blood:Aplastic anemia. Nutritional and
Gross Metabolic:Weight loss or decreased weight gain.
LD50 Subcutaneous - Rat - > 46 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity). Blood:Aplastic anemia. Nutritional and
Gross Metabolic:Weight loss or decreased weight gain.
LD50 Intravenous - Mouse - > 0,076 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity). Blood:Aplastic anemia. Nutritional and
Gross Metabolic:Weight loss or decreased weight gain. LD50 Subcutaneous - Mouse - > 0,290 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity). Blood:Aplastic anemia. Nutritional and
Gross Metabolic:Weight loss or decreased weight gain.
Skin corrosion/irritation
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitisation
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available Additional Information
RTECS: Not available
ECOLOGICAL INFORMATION12.1 Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Other adverse effects
No data available
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed
professional waste disposal service to dispose of this material. Dissolve or mix the material with a
combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product
TRANSPORT INFORMATION14.1 UN number
ADR/RID: 2811 IMDG: 2811 IATA: 2811
14.2 UN proper shipping name
ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (Flunisolide)
IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Flunisolide)
IATA: Toxic solid, organic, n.o.s. (Flunisolide)
14.3 Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group
ADR/RID: I IMDG: I IATA: I
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
REGULATORY INFORMATIONThis safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!