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Chlorpromazine hydrochloride Solution (Solvent: Acetonitrile)
| Item number | 686133 |
| CAS | 69-09-0 |
| Formula | C17H20Cl2N2S |
| Molecular weight | 355,33 g/mol |
| Quantity | 1X5ML |
| Concentration | 100 µg/ml |
| Solvent | Acetonitrile |
| storage conditions | 4 °C |
| CoA / MSDS | Retrieve CoA Retrieve MSDS |
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Part of Product groups:
Product Variations:
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
 | 677954 | 1X250MG | Please log in. | |
Chlorpromazine hydrochloride solution |  | 686133 | 1X5ML | Please log in. |
 | 679586 | 1X10MG | Please log in. | |
D6-Chlorpromazine hydrochloride solution |  | 690882 | 1X1ML |
| Safety Data Sheet | according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 07.11.2024 |
| IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING | |
| Product name: | Chlorpromazine hydrochloride |
| Catalog No.: | 686133 |
| Relevant identified uses of the substance or mixture | Identified: Laboratory chemical uses: R&D |
| Uses advised against: | HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com |
| Emergency telephone number | HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours. |
| HAZARDS IDENTIFICATION | 2.1. Classification of the substance or mixture Regulation (EC) No 1272/2008 Acute toxicity - Oral Category 3 - (H301) Acute toxicity - Inhalation (Dusts/Mists) Category 2 - (H330) Skin corrosion/irritation Category 2 - (H315) Serious eye damage/eye irritation Category 2 - (H319) Skin sensitisation Category 1 - (H317) Reproductive toxicity Category 1B - (H360) Effects on or via lactation Yes - (H362) Specific target organ toxicity — single exposure Category 3 - (H336) Specific target organ toxicity — repeated exposure Category 2 - (H373) Chronic aquatic toxicity Category 3 - (H412) |
| Label elements | |
| Pictogram | GHS06 skull skull GHS08 silhouete silhouete |
| 200-701-3 Contains Chlorpromazine Hydrochloride Signal word Danger Hazard statements H301 - Toxic if swallowed H315 - Causes skin irritation H317 - May cause an allergic skin reaction H319 - Causes serious eye irritation H330 - Fatal if inhaled H336 - May cause drowsiness or dizziness H360 - May damage fertility or the unborn child H362 - May cause harm to breast-fed children H373 - May cause damage to organs through prolonged or repeated exposure H412 - Harmful to aquatic life with long lasting effects Precautionary Statements - EU (§28, 1272/2008) P201 - Obtain special instructions before use P260 - Do not breathe dust/fume/gas/mist/vapours/spray P263 - Avoid contact during pregnancy and while nursing P280 - Wear protective gloves/protective clothing/eye protection/face protection P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P310 - Immediately call a POISON CENTER or doctor P403 + P233 - Store in a well-ventilated place. Keep container tightly closed 2.3. Other hazards No information available. This substance does not meet the PBT/vPvB criteria of REACH, annex XIII. | |
| COMPOSITION/INFORMATION ON INGREDIENTS | Chemical name: Chlorpromazine Hydrochloride 69-09-0 Weight-%: 100 REACH registration number: - EC No: 200-701-3 Classification according to Regulation (EC) No. 1272/2008 [CLP]: Acute Tox. 2 (H330) Acute Tox. 3 (H301) Skin Irrit. 2 (H315) Eye Irrit. 2 (H319) Skin Sens. 1 (H317) Repr. 1B (H360) Lact. (H362) STOT SE 3 (H336) STOT RE 2 (H373) Aquatic Chronic 3(H412) Specific concentrationlimit (SCL): - M-Factor: - M-Factor (long-term): - Full text of H- and EUH-phrases: see section 16 Acute Toxicity Estimate If LD50/LC50 data is not available or does not correspond to the classification category, then the appropriate conversion value from CLP Annex I, Table 3.1.2, is used to calculate the acute toxicity estimate (ATEmix) for classifying a mixture based on its components Chemical name: Chlorpromazine Hydrochloride 69-09-0 Oral LD50 mg/kg: 145 Dermal LD50 mg/kg: No data available Inhalation LC50 - 4 hour - dust/mist - mg/L: No data available Inhalation LC50 - 4 hour - vapour - mg/L: No data available Inhalation LC50 - 4hour - gas - ppm : No data available This product does not contain candidate substances of very high concern at a concentration >=0.1% (Regulation (EC) No. 1907/2006 (REACH), Article 59) |
| Formula | C17H20Cl2N2S |
| Molecular Weight (g/mol) | 355.33 |
| CAS-No. | 69-09-0 |
| FIRST AID MEASURES | 4.1. Description of first aid measures General advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required. Inhalation If breathing has stopped, give artificial respiration. Get medical attention immediately Remove to fresh air. Do not breathe dust. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. If breathing is difficult, (trained personnel should) give oxygen. IF exposed or concerned: Get medical advice/attention. Get medical attention immediately if symptoms occur. Eye contact Remove contact lenses, if present and easy to do. Continue rinsing. Keep eye wide open while rinsing. Do not rub affected area. Get medical attention if irritation develops and persists. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Skin contact May cause an allergic skin reaction. In the case of skin irritation or allergic reactions see a doctor. Wash off immediately with soap and plenty of water for at least 15 minutes. Ingestion Do NOT induce vomiting. Rinse mouth. Never give anything by mouth to an unconscious person. Call a doctor or poison control centre immediately. Self-protection of the first aider Avoid contact with skin, eyes or clothing. Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination. Do not breathe dust. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Use personal protective equipment as required. See section 8 for more information. 4.2. Most important symptoms and effects, both acute and delayed Symptoms Inhalation of high vapour concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting. Coughing and/ or wheezing. Difficulty in breathing. Itching. Rashes. Hives. May cause redness and tearing of the eyes. Burning sensation 4.3. Indication of any immediate medical attention and special treatment needed Note to doctors May cause sensitisation in susceptible persons. Treat symptomatically. |
| FIRE-FIGHTING MEASURES | Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Large Fire CAUTION: Use of water spray when fighting fire may be inefficient. Unsuitable extinguishing media Do not scatter spilled material with high pressure water streams. 5.2. Special hazards arising from the substance or mixture Specific hazards arising from the Product is or contains a sensitiser. May cause sensitisation by skin contact chemical 5.3. Advice for firefighters Special protective equipment and precautions for fire-fighters Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear. Use personal protection equipment. |
| ACCIDENTAL RELEASE MEASURES | 6.1. Personal precautions, protective equipment and emergency procedures Personal precautions Ensure adequate ventilation. Avoid contact with skin, eyes or clothing. Avoid generation of dust. Do not breathe dust. Use personal protective equipment as required. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. Other information Refer to protective measures listed in Sections 7 and 8. For emergency responders Use personal protection recommended in Section 8. 6.2. Environmental precautions Environmental precautions Prevent further leakage or spillage if safe to do so. Should not be released into the environment. Do not allow to enter into soil/subsoil. Prevent product from entering drains. 6.3. Methods and material for containment and cleaning up Methods for containment Prevent further leakage or spillage if safe to do so. Methods for cleaning up Take up mechanically, placing in appropriate containers for disposal. Prevention of secondary hazards Clean contaminated objects and areas thoroughly observing environmental regulations. 6.4. Reference to other sections Reference to other sections See section 8 for more information. See section 13 for more information. |
| HANDLING AND STORAGE | 7.1. Precautions for safe handling Advice on safe handling Handle in accordance with good industrial hygiene and safety practice. In case of insufficient ventilation, wear suitable respiratory equipment. Avoid breathing vapours or mists. Avoid contact with skin, eyes or clothing. Handle product only in closed system or provide appropriate exhaust ventilation. Do not eat, drink or smoke when using this product. Take off contaminated clothing and wash it before reuse. Remove contaminated clothing and shoes General hygiene considerations Do not breathe dust. Take off contaminated clothing and wash it before reuse. Contaminated work clothing should not be allowed out of the workplace. Regular cleaning of equipment, work area and clothing is recommended. Wash hands before breaks and immediately after handling the product. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. 7.2. Conditions for safe storage, including any incompatibilities Storage Conditions Keep containers tightly closed in a dry, cool and well-ventilated place. Keep out of the reach of children. Please refer to the manufacturers certificate for specific storage and transport temperature conditions. Store only in the original receptacle unless other advice is given on the CoA. 7.3. Specific end use(s) Risk Management Methods (RMM) The information required is contained in this Safety Data Sheet. |
| EXPOSURE CONTROLS/PERSONAL PROTECTION | Exposure Limits Chemical name: Chlorpromazine Hydrochloride 69-09-0 France: - Germany: Skin sensitizer Germany MAK: - Greece: - Hungary: - Biological occupational exposure limits This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies Derived No Effect Level (DNEL) No information available. Predicted No Effect Concentration (PNEC) No information available. 8.2. Exposure controls Personal protective equipment Eye/face protection If splashes are likely to occur, wear safety glasses with side-shields. Avoid contact with eyes. Wear safety glasses with side shields (or goggles). Hand protection Wear suitable gloves. Impervious gloves. The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374. Wear protective Viton™ gloves. Skin and body protection Long sleeved clothing. Wear suitable protective clothing. Respiratory protection When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. General hygiene considerations Do not breathe dust. Take off contaminated clothing and wash it before reuse. Contaminated work clothing should not be allowed out of the workplace. Regular cleaning of equipment, work area and clothing is recommended. Wash hands before breaks and immediately after handling the product. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. Environmental exposure controls Do not allow into any sewer, on the ground or into any body of water. |
| PHYSICAL AND CHEMICAL PROPERTIES | 9.1. Information on basic physical and chemical properties Physical state Solid Appearance Solid Colour white Odour No information available. Odour threshold No information available Property Values Remarks • Method Melting point / freezing point 194 - 199 °C None known Boiling point / boiling range No data available None known Flammability (solid, gas) No data available None known Flammability Limit in Air None known Upper flammability or explosive limits No data available Lower flammability or explosive limits No data available Flash point No data available None known Autoignition temperature No data available None known Decomposition temperature None known pH No data available None known pH (as aqueous solution) No data available No information available Kinematic viscosity No data available None known Dynamic viscosity No data available None known Water solubility Soluble in water None known Solubility(ies) Alcohol Partition coefficient No data available None known Vapour pressure No data available None known Relative density No data available None known Bulk density No data available Liquid Density No data available Relative vapour density No data available None known Particle characteristics Particle Size No information available Particle Size Distribution No information available 9.2. Other information Molecular weight 355.32 Molecular formula C17 H19 Cl N2 S . HCl 9.2.1. Information with regards to physical hazard classes Not applicable 9.2.2. Other safety characteristics No information available |
| STABILITY AND REACTIVITY | 10.1. Reactivity Reactivity No information available. 10.2. Chemical stability Stability Stable under normal conditions. Explosion data Sensitivity to mechanical impact None. Sensitivity to static discharge None. 10.3. Possibility of hazardous reactions Possibility of hazardous reactions None under normal processing. 10.4. Conditions to avoid Conditions to avoid Excessive heat. 10.5. Incompatible materials Incompatible materials Strong acids. Strong bases. Strong oxidising agents. Hazardous decomposition products None known based on information supplied. |
| TOXICOLOGICAL INFORMATION | 11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008 Information on likely routes of exposure Product Information Inhalation Specific test data for the substance or mixture is not available. Fatal if inhaled. (based on components). Eye contact Specific test data for the substance or mixture is not available. Causes serious eye irritation. (based on components). May cause redness, itching, and pain. Skin contact Specific test data for the substance or mixture is not available. May cause sensitisation by skin contact. Repeated or prolonged skin contact may cause allergic reactions with susceptible persons. (based on components). Causes skin irritation. Ingestion Specific test data for the substance or mixture is not available. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhoea. Toxic if swallowed. (based on components). Symptoms related to the physical, chemical and toxicological characteristics Symptoms May cause redness and tearing of the eyes. Inhalation of high vapour concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting. Coughing and/ or wheezing. Difficulty in breathing. Itching. Rashes. Hives. Redness. Numerical measures of toxicity Acute toxicity Component Information Chemical name: Chlorpromazine Hydrochloride Oral LD50 = 145 mg/kg ( Rat ) Dermal LD50: - Inhalation LC50 = 40 mg/m3 ( Rat ) 2 h Delayed and immediate effects as well as chronic effects from short and long-term exposure Skin corrosion/irritation Classification based on data available for ingredients. Irritating to skin. Serious eye damage/eye irritation Classification based on data available for ingredients. Causes serious eye irritation. Respiratory or skin sensitisation May cause sensitisation by skin contact. Germ cell mutagenicity No information available. Carcinogenicity No information available. Reproductive toxicity Contains a known or suspected reproductive toxin. Classification based on data available for ingredients. May damage fertility or the unborn child. May cause harm to breast-fed children. STOT - single exposure May cause drowsiness or dizziness. STOT - repeated exposure May cause damage to organs through prolonged or repeated exposure. Aspiration hazard No information available. 11.2. Information on other hazards 11.2.1. Endocrine disrupting properties Endocrine disrupting properties No information available. 11.2.2. Other information Other adverse effects No information available. |
| ECOLOGICAL INFORMATION | 12.1. Toxicity Ecotoxicity Harmful to aquatic life with long lasting effects. 12.2. Persistence and degradability Persistence and degradability No information available. 12.3. Bioaccumulative potential Bioaccumulation No information available. 12.4. Mobility in soil Mobility in soil No information available. 12.5. Results of PBT and vPvB assessment PBT and vPvB assessment The product does not contain any substance(s) classified as PBT or vPvB. 12.6. Endocrine disrupting properties Endocrine disrupting properties No information available. 12.7. Other adverse effects No information available. |
| DISPOSAL CONSIDERATIONS | 13.1. Waste treatment methods Waste from residues/unused products Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation. Contaminated packaging Do not reuse empty containers. |
| TRANSPORT INFORMATION | IATA 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (Chlorpromazine Hydrochloride) 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2811, Toxic solid, organic, n.o.s. (Chlorpromazine Hydrochloride), 6.1, II 14.5 Environmental hazards Not applicable 14.6 Special precautions for user Special Provisions A3, A5 ERG Code 6L IMDG 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (Chlorpromazine Hydrochloride) 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2811, Toxic solid, organic, n.o.s. (Chlorpromazine Hydrochloride), 6.1, II 14.5 Marine pollutant NP 14.6 Special precautions for user Special Provisions 274 EmS-No F-A, S-A No information available 14.7 Maritime transport in bulk according to IMO instruments No information available RID 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (Chlorpromazine Hydrochloride) 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2811, Toxic solid, organic, n.o.s. (Chlorpromazine Hydrochloride), 6.1, II 14.5 Environmental hazards Not applicable 14.6 Special precautions for user Special Provisions 274, 614 Classification code T2 ADR 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (Chlorpromazine Hydrochloride) 14.3 Transport hazard class(es) 6.1 14.4 Packing group II Description UN2811, Toxic solid, organic, n.o.s. (Chlorpromazine Hydrochloride), 6.1, II, (D/E) 14.5 Environmental hazards Not applicable 14.6 Special precautions for user Special Provisions 274, 614 Classification code T2 Tunnel restriction code (D/E) |
| REGULATORY INFORMATION | 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture Water hazard class (WGK) strongly hazardous to water (WGK 3) Poland SDS created according to the following Polish regulation: Act of February 25, 2011 on chemical substances and their mixtures (Journal of Laws of 2018, item 143, as amended). Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), establishing the European Chemicals Agency (EC) as amended. Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labeling and packaging of substances and mixtures, as amended. Regulation of the Minister of Health of 10 August 2012 on the criteria and method of classifying chemical substances and their mixtures (Journal of Laws of 2012, item 1018). Regulation of the Minister of Health of 20 April 2012 on labeling packaging of hazardous substances and mixtures and some mixtures (Journal of Laws of 2012, item 445). Regulation of the Minister of Family, Labor and Social Policy of 12 June 2018 on the maximum allowable concentrations and intensities of factors harmful to health in the work environment (Journal of Laws of 2018, item 1286). Announcement of the Minister of Economy, Labor and Social Policy of August 28, 2003 on the publication of the unified text of the Ordinance of the Minister of Labor and Social Policy on general health and safety at work regulations (Journal of Laws of 2003, No. 169, item 1650) . Regulation of the Minister of Health of 30 December 2004 on occupational safety and health related to the presence of chemical agents in the workplace (Journal of Laws of 2005, No. 11, item 86). Act of December 14, 2012 on waste (Journal of Laws of 2013, item 21) Regulation of the Minister of Health of December 30, 2004 on occupational health and safety related to the presence of chemical agents in the workplace (Journal U. of 2005, No. 11, item 86). Waste Act of December 14, 2012 (Journal of Laws of 2013, item 21). Act of 13 June 2013 on the management of packaging and packaging waste, Journal of Laws 2013, item 888). Government statement of September 24, 2002 - European Agreement on the International Carriage of Dangerous Goods by Road (ADR) (Journal of Laws No. 194, item 1629 and Journal of Laws of 2003, No. 207, item 2013 and 2014). European Union Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Authorisations and/or restrictions on use: This product does not contain substances subject to authorisation (Regulation (EC) No. 1907/2006 (REACH), Annex XIV) This product does not contain substances subject to restriction (Regulation (EC) No. 1907/2006 (REACH), Annex XVII) DIRECTIVE (EU) 2021/1187 on the marketing and use of explosives precursors Not applicable Persistent Organic Pollutants Not applicable Dangerous substance category per Seveso Directive (2012/18/EU) H2 - ACUTE TOXIC Ozone-depleting substances (ODS) regulation (EC) 1005/2009 Not applicable International Inventories TSCA Contact supplier for inventory compliance status DSL/NDSL Contact supplier for inventory compliance status EINECS/ELINCS Contact supplier for inventory compliance status ENCS Contact supplier for inventory compliance status IECSC Contact supplier for inventory compliance status KECL Contact supplier for inventory compliance status PICCS Contact supplier for inventory compliance status AICS Contact supplier for inventory compliance status Legend: TSCA - United States Toxic Substances Control Act Section 8(b) Inventory DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances ENCS - Japan Existing and New Chemical Substances IECSC - China Inventory of Existing Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances PICCS - Philippines Inventory of Chemicals and Chemical Substances AICS - Australian Inventory of Chemical Substances 15.2. Chemical safety assessment Chemical Safety Report A Chemical Safety Assessment has been carried out for this substance |
| OTHER INFORMATION | The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only! |