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Valifenalate

ISO 17034 Reference Material

Item number674486
CAS283159-90-0
FormulaC19H27ClN2O5
Molecular weight398,89 g/mol
Quantity 1X25MG
storage conditions4 °C
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Valifenalate

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ISO 17034 Reference Material

Valifenalate

Valifenalate

674486
283159-90-0

1X25MG

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Valifenalate solution
Concentration: 100 µg/ml
Solvent: Acetonitrile

Valifenalate solution

681809
283159-90-0

1X1ML

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ISO 17034 Certified Reference Material

Valifenalate

Valifenalate

690139
283159-90-0

1X10MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 15.01.2025
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Valifenalate
Catalog No.:674486
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture Carcinogenicity, (Category 2)
H351: Suspected of causing cancer. Long-term (chronic) aquatic
hazard, (Category 2)
H411: Toxic to aquatic life with long lasting effects.
Label elements
PictogramGHS08 silhouete
silhouete
GHS09 Aquatic-pollut-red
Aquatic-pollut-red
2.2 Label elements
Signal Word Warning
Hazard Statements
H351 Suspected of causing cancer.
H411 Toxic to aquatic life with long lasting effects.
Precautionary Statements
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P391 Collect spillage.
P405 Store locked up.
Supplemental Hazard Statements none.
2.3 Other hazards:
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
Ecological information:
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Toxicological information:
The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Formula : C19H27ClN2O5
Molecular weight : 398,88 g/mol
CAS-No. : 283159-90-0
Index-No. : 607-762-00-9
Component: Valifenalate, CAS-No.283159-90-0, Index-No.:
607-762-00-9
Classification:
Carc. 2; Aquatic Chronic
2; H351, H411
Concentration:
<= 100 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
FormulaC19H27ClN2O5
Molecular Weight (g/mol)398.89
CAS-No.283159-90-0
FIRST AID MEASURES4.1 Description of first-aid measures
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact
lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a
physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Nitrogen oxides (NOx)
Hydrogen chloride gas
Combustible.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by
keeping a safe distance or by wearing suitable protective clothing.
5.4 Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire
extinguishing water from contaminating surface water or the ground water system.
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact.
Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures,
consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid
generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands
and face after working with substance.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Dry. Keep locked up or in an area accessible only to qualified or authorized
persons.
Air and moisture sensitive. Store under inert gas.
Storage class
Storage class (TRGS 510): 11: Combustible Solids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN 16523-1 please
contact the supplier of CE-approved gloves.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L
Body Protection
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following
standards: DIN EN 143, DIN 14387 and other accompanying standards relating to
the used respiratory protection system.
Recommended Filter type: Filter type P3
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Physical state powder
b) Color white
c) Odor odorless
d) Melting
point/freezing point
147 °C
e) Initial boiling point
and boiling range
367 °C at 1020 hPa
f) Flammability (solid,
gas)
No data available
g) Upper/lower
flammability or
explosive limits
No data available
h) Flash point No data available
i) Autoignition
temperature
not auto-flammable
j) Decomposition
temperature
No data available
k) pH No data available
l) Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
m) Water solubility 0,024 g/l at 20 °C
n) Partition coefficient:
n-octanol/water
log Pow: 3,0 - 3,1
o) Vapor pressure No data available
p) Density 1,25 g/cm3
Relative density No data available
q) Relative vapor
density
r) Particle
characteristics
No data available
s) Explosive properties No data available
t) Oxidizing properties none
9.2 Other safety information
Solubility in other
solvents
Acetone 29,3 g/l at 20 °C
STABILITY AND REACTIVITY10.1 Reactivity
The following applies in general to flammable organic substances and mixtures: in
correspondingly fine distribution, when whirled up a dust explosion potential may generally
be assumed.
10.2 Chemical stability
Decomposes upon contact with air.
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
no information available
10.5 Incompatible materials
Oxidizing agents
10.6 Hazardous decomposition products
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - > 5.000 mg/kg
Inhalation: No data available
LD50 Dermal - Rat - > 2.000 mg/kg
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
Suspected of causing cancer.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information
Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain
components considered to have endocrine
disrupting properties according to REACH Article
57(f) or Commission Delegated regulation (EU)
2017/2100 or Commission Regulation (EU)
2018/605 at levels of 0.1% or higher.
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
ECOLOGICAL INFORMATION12.1 Toxicity
Toxicity to fish LC50 - Oncorhynchus mykiss (rainbow trout) - > 100 mg/l - 96 h
Toxicity to daphnia
and other aquatic
invertebrates
LC50 - Daphnia - > 100 mg/l - 48 h
Toxicity to algae EC50 - Algae - > 100 mg/l - 72 h
Toxicity to
fish(Chronic toxicity)
Remarks: The GHS classification specified by the authority
(Valifenalate)
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components
considered to have endocrine disrupting properties
according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.
12.7 Other adverse effects
Stability in water DT50 - 7,62 h pH 7
Remarks: Hydrolyzes slowly on contact with water.
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
No data available
TRANSPORT INFORMATION14.1 UN number
ADR/RID: 3077 IMDG: 3077 IATA: 3077
14.2 UN proper shipping name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Valifenalate)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Valifenalate)
IATA: Environmentally hazardous substance, solid, n.o.s. (Valifenalate)
14.3 Transport hazard class(es)
ADR/RID: 9 IMDG: 9 IATA: 9
14.4 Packaging group
ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
14.6 Special precautions for user
Tunnel restriction code : (-)
Further information
EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and
combination packagings containing inner packagings with Dangerous Goods > 5L for liquids
or > 5kg for solids.Packages smaller than or equal to 5 kg / L , not dangerous goods of
Class 9
REGULATORY INFORMATION15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
Authorisations and/or restrictions on use
National legislation
Seveso III: Directive 2012/18/EU of the
European Parliament and of the Council
on the control of major-accident hazards
involving dangerous substances.
E2
ENVIRONMENTAL HAZARDS
Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or
stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!