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Sedaxane

ISO 17034 Reference Material

Item number678632
CAS874967-67-6
FormulaC18H19F2N3O
Molecular weight331,36 g/mol
Quantity 1X10MG
storage conditions4 °C
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Sedaxane

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Sedaxane solution
Concentration: 100 µg/ml
Solvent: Acetonitrile

Sedaxane solution

678328
874967-67-6

1X1ML

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ISO 17034 Reference Material

Sedaxane

Sedaxane

678632
874967-67-6

1X10MG

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Sedaxane solution
Concentration: 10.0 µg/ml
Solvent: Acetonitrile

Sedaxane solution

680927
874967-67-6

1X10ML

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ISO 17034 Certified Reference Material

Sedaxane

Sedaxane

692068
874967-67-6

1X10MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 04.09.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Sedaxane
Catalog No.:678632
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Acute aquatic toxicity (Category 1)
Chronic aquatic toxicity (Category 1)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Label elements
PictogramGHS09 Aquatic-pollut-red
Aquatic-pollut-red
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram Signal word Warning
Hazard statement(s)
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P273 Avoid release to the environment.
P501 Dispose of contents/ container to an approved waste disposal plant.
Supplemental Hazard
Statements
none
According to European Directive 67/548/EEC as amended.
Hazard symbol(s) R-phrase(s)
R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s)
S60 This material and its container must be disposed of as hazardous waste.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
2.3 Other hazards - none
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Formula : C18H19F2N3O
Molecular Weight : 331,36 g/mol
Component Concentration
Sedaxane, mixture of isomers
CAS-No.
874967-67-6
-
FormulaC18H19F2N3O
Molecular Weight (g/mol)331.36
CAS-No.874967-67-6
FIRST AID MEASURES4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
4.3 Indication of any immediate medical attention and special treatment needed
no data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx), Hydrogen fluoride
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
no data available
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure
adequate ventilation. Avoid breathing dust.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
7.3 Specific end uses
no data available
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands. Body Protection
impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher
level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges.
Use respirators and components tested and approved under appropriate government standards
such as NIOSH (US) or CEN (EU).
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: crystalline
Colour: white
b) Odour no data available
c) Odour Threshold no data available
d) pH 5,9 at 10 g/l at 25 °C
e) Melting point/freezing
point
Melting point/range: 121,4 °C
f) Initial boiling point and
boiling range
> 270 °C
g) Flash point no data available
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower
flammability or
explosive limits
no data available
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density no data available
n) Water solubility 0,014 g/l at 25 °C
o) Partition coefficient: noctanol/
water
log Pow: 3,3 at 25 °C
p) Autoignition
temperature
400 °C
q) Decomposition
temperature
no data available
r) Viscosity no data available
s) Explosive properties Not explosive
t) Oxidizing properties The substance or mixture is not classified as oxidizing.
9.2 Other safety information
Solubility in other
solvents
Methanol 110 g/l at 25 °C
STABILITY AND REACTIVITY10.1 Reactivity
no data available
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
no data available
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Strong oxidizing agents 10.6 Hazardous decomposition products
Other decomposition products - no data available
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - rat - female - 5.000 mg/kg
LD50 Oral - rat - male - > 5.244 mg/kg
LD50 Dermal - rat - > 2.000 mg/kg
Skin corrosion/irritation
Skin - rabbit - No skin irritation
Serious eye damage/eye irritation
Eyes - rabbit - Mild eye irritation
Respiratory or skin sensitization
mouse - Did not cause sensitization on laboratory animals.
Germ cell mutagenicity
Animal testing did not show any mutagenic effects.
Carcinogenicity
Animal testing did not show any carcinogenic effects.
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Did not show teratogenic effects in animal experiments.
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes Causes eye irritation.
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
Additional Information
RTECS: Not available
ECOLOGICAL INFORMATION12.1 Toxicity
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0,62 mg/l - 96 h
Toxicity to daphnia and
other aquatic
invertebrates
EC50 - Daphnia magna (Water flea) - 6,10 mg/l - 48 h
Toxicity to algae EbC50 - Pseudokirchneriella subcapitata - 1,9 mg/l - 96 h
Toxicity to bacteria EC50 - Sludge Treatment - > 1.000 mg/l - 3 h 12.2 Persistence and degradability
Biodegradability Result: - According to the results of tests of biodegradability this product is not
readily biodegradable.
12.3 Bioaccumulative potential
no data available
12.4 Mobility in soil
no data available
12.5 Results of PBT and vPvB assessment
no data available
12.6 Other adverse effects
Very toxic to aquatic life with long lasting effects.
no data available
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product
TRANSPORT INFORMATION14.1 UN number
ADR/RID: 3077 IMDG: 3077 IATA: 3077
14.2 UN proper shipping name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Sedaxane, mixture of
isomers)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Sedaxane, mixture of
isomers)
IATA: Environmentally hazardous substance, solid, n.o.s. (Sedaxane, mixture of isomers)
14.3 Transport hazard class(es)
ADR/RID: 9 IMDG: 9 IATA: 9
14.4 Packaging group
ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
14.6 Special precautions for user
Further information
EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination
packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.
REGULATORY INFORMATIONThis safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
15.2 Chemical Safety Assessment
no data available
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!