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(-)-Nicotine
| Item number | 674315 |
| CAS | 54-11-5 |
| Formula | C10H14N2 |
| Molecular weight | 162,23 g/mol |
| Quantity | 1X500MG |
| storage conditions | 20 °C |
| CoA / MSDS | Retrieve CoA Retrieve MSDS |
Price | Please log in. |
Part of Product groups:
Product Variations:
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
 | 674315 | 1X500MG | Please log in. | |
(-)-Nicotine solution |  | 679299 | 1X10ML | Please log in. |
(-)-Nicotine solution |  | 679982 | 1X1ML | Please log in. |
 | 685028 | 1X10MG | Please log in. | |
D3-Nicotine solution |  | 685029 | 1X1ML | Please log in. |
| Safety Data Sheet | according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 26.12.2024 |
| IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING | |
| Product name: | (-)-Nicotine |
| Catalog No.: | 674315 |
| Relevant identified uses of the substance or mixture | Identified: Laboratory chemical uses: R&D |
| Uses advised against: | HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com |
| Emergency telephone number | HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours. |
| HAZARDS IDENTIFICATION | 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Dermal (Category 1), H310 Acute toxicity, Oral (Category 3), H301 Chronic aquatic toxicity (Category 2), H411 Classification according to EU Directives 67/548/EEC or 1999/45/EC T+ Very toxic R27 T Toxic R25 N Dangerous for the environment R51/53 |
| Label elements | |
| Pictogram | GHS06 skull skull GHS09 Aquatic-pollut-red Aquatic-pollut-red |
| 2.2 Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal word Danger Hazard statement(s) H301 Toxic if swallowed. H310 Fatal in contact with skin. H411 Toxic to aquatic life with long lasting effects. Precautionary statement(s) P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P302 + P350 IF ON SKIN: Gently wash with plenty of soap and water. P310 Immediately call a POISON CENTER or doctor/ physician. Supplemental Hazard Statements none 2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. | |
| COMPOSITION/INFORMATION ON INGREDIENTS | 3.1 Substances Synonyms : L(−)-3-(N-Methyl)-α-pyrrolidyl)pyridin (−)-1-Methyl-2-(3-pyridyl)pyrrolidine Formula : C10H14N2 Molecular weight : 162,23 g/mol CAS-No. : 54-11-5 EC-No. : 200-193-3 Index-No. : 614-001-00-4 Hazardous ingredients according to Regulation (EC) No 1272/2008 Component Classification Concentration (-)-Nicotine CAS-No. EC-No. Index-No. 54-11-5 200-193-3 614-001-00-4 Acute Tox. 3; Acute Tox. 1; Aquatic Acute 1; Aquatic Chronic 2; H301, H310, H400, H411 <= 100 % Hazardous ingredients according to Directive 1999/45/EC Component Classification Concentration (-)-Nicotine CAS-No. EC-No. Index-No. 54-11-5 200-193-3 614-001-00-4 T+, N, R25 - R27 - R51/53 <= 100 % |
| Formula | C10H14N2 |
| Molecular Weight (g/mol) | 162.23 |
| CAS-No. | 54-11-5 |
| FIRST AID MEASURES | 4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician In case of eye contact Flush eyes with water as a precaution. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available |
| FIRE-FIGHTING MEASURES | 5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. 5.2 Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides (NOx) 5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary. 5.4 Further information No data available |
| ACCIDENTAL RELEASE MEASURES | 6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. For personal protection see section 8. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. 6.3 Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. 6.4 Reference to other sections For disposal see section 13 |
| HANDLING AND STORAGE | 7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas. Hygroscopic. Air and light sensitive. 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| EXPOSURE CONTROLS/PERSONAL PROTECTION | 8.1 Control parameters Components with workplace control parameters 8.2 Exposure controls Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided |
| PHYSICAL AND CHEMICAL PROPERTIES | 9.1 Information on basic physical and chemical properties a) Appearance Form: clear, liquid Colour: dark brown b) Odour No data available c) Odour Threshold No data available d) pH 10,2 e) Melting point/freezing point Melting point/range: -79 °C f) Initial boiling point and boiling range 247 °C at 993 hPa g) Flash point 101 °C - closed cup h) Evaporation rate No data available i) Flammability (solid, gas) No data available j) Upper/lower flammability or explosive limits No data available k) Vapour pressure 0,051 hPa at 25 °C l) Vapour density 5,6 - (Air = 1.0) m) Relative density 1,010 g/cm3 n) Water solubility completely miscible o) Partition coefficient: noctanol/ water log Pow: 1,17 p) Auto-ignition temperature No data available q) Decomposition temperature No data available r) Viscosity No data available s) Explosive properties No data available t) Oxidizing properties No data available 9.2 Other safety information Relative vapour density 5,6 - (Air = 1.0) |
| STABILITY AND REACTIVITY | 10.1 Reactivity No data available 10.2 Chemical stability Stable under recommended storage conditions. 10.3 Possibility of hazardous reactions No data available 10.4 Conditions to avoid No data available 10.5 Incompatible materials Strong oxidizing agents 10.6 Hazardous decomposition products Other decomposition products - No data available In the event of fire: see section 5 |
| TOXICOLOGICAL INFORMATION | 11.1 Information on toxicological effects Acute toxicity LD50 Oral - Rat - 50 mg/kg Dermal: No data available Skin corrosion/irritation No data available Serious eye damage/eye irritation No data available Respiratory or skin sensitisation No data available Germ cell mutagenicity No data available Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity Possible risk of congenital malformation in the fetus. Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available Additional Information RTECS: QS5250000 prolonged or repeated exposure can cause:, Vomiting, Diarrhoea, Convulsions, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated |
| ECOLOGICAL INFORMATION | 12.1 Toxicity Toxicity to fish LC50 - Oncorhynchus mykiss (rainbow trout) - 4 mg/l - 96,0 h Toxicity to daphnia and other aquatic invertebrates EC50 - Daphnia magna (Water flea) - 0,24 mg/l - 48 h 12.2 Persistence and degradability No data available 12.3 Bioaccumulative potential No data available 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. 12.6 Other adverse effects Very toxic to aquatic life |
| DISPOSAL CONSIDERATIONS | 13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product |
| TRANSPORT INFORMATION | 14.1 UN number ADR/RID: 1654 IMDG: 1654 IATA: 1654 14.2 UN proper shipping name ADR/RID: NICOTINE IMDG: NICOTINE IATA: Nicotine 14.3 Transport hazard class(es) ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1 14.4 Packaging group ADR/RID: II IMDG: II IATA: II 14.5 Environmental hazards ADR/RID: yes IMDG Marine pollutant: yes IATA: no 14.6 Special precautions for user No data available |
| REGULATORY INFORMATION | This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture No data available 15.2 Chemical Safety Assessment For this product a chemical safety assessment was not carried out |
| OTHER INFORMATION | The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only! |