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1,4-Dioxane
| Item number | 676138 |
| CAS | 123-91-1 |
| Formula | C4H8O2 |
| Molecular weight | 88,11 g/mol |
| Quantity | 1X5ML |
| storage conditions | 20 °C |
| CoA / MSDS | Retrieve CoA Retrieve MSDS |
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Part of Product groups:
Product Variations:
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
 | 686088 | 1X5ML | Please log in. | |
 | 676138 | 1X5ML | Please log in. | |
 | 681329 | 1X250MG | Please log in. | |
D8-1,4-Dioxane solution |  | 682029 | 1X1ML | Please log in. |
| Safety Data Sheet | according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 19.11.2024 |
| IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING | |
| Product name: | 1,4-Dioxane |
| Catalog No.: | 676138 |
| Relevant identified uses of the substance or mixture | Identified: Laboratory chemical uses: R&D |
| Uses advised against: | HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com |
| Emergency telephone number | HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours. |
| HAZARDS IDENTIFICATION | 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 2), H225 Eye irritation (Category 2), H319 Carcinogenicity (Category 2), H351 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 |
| Label elements | |
| Pictogram | flamme flamme GHS07 exclam exclam GHS08 silhouete silhouete |
| 2.2 Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H351 Suspected of causing cancer. Precautionary statement(s) P201 Obtain special instructions before use. P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. Supplemental Hazard information (EU) EUH019 May form explosive peroxides. EUH066 Repeated exposure may cause skin dryness or cracking. 2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. | |
| COMPOSITION/INFORMATION ON INGREDIENTS | 3.1 Substances Synonyms : Dioxane Diethylene oxide Formula : C4H8O2 Molecular weight : 88,11 g/mol CAS-No. : 123-91-1 EC-No. : 204-661-8 Index-No. : 603-024-00-5 Component Classification Concentration 1,4-Dioxane Flam. Liq. 2; Eye Irrit. 2; Carc. 2; STOT SE 3; H225, H319, H351, H335 Concentration limits: >= 20 %: STOT SE 3, H335; <= 100 % |
| Formula | C4H8O2 |
| Molecular Weight (g/mol) | 88.11 |
| CAS-No. | 123-91-1 |
| FIRST AID MEASURES | 4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available |
| FIRE-FIGHTING MEASURES | 5.1 Extinguishing media Suitable extinguishing media Dry powder Dry sand Unsuitable extinguishing media Do NOT use water jet. 5.2 Special hazards arising from the substance or mixture Carbon oxides 5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary. 5.4 Further information Use water spray to cool unopened containers |
| ACCIDENTAL RELEASE MEASURES | 6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13). 6.4 Reference to other sections For disposal see section 13. |
| HANDLING AND STORAGE | 7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store in cool place. 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| EXPOSURE CONTROLS/PERSONAL PROTECTION | |
| PHYSICAL AND CHEMICAL PROPERTIES | 9.1 Information on basic physical and chemical properties a) Appearance Form: liquid Colour: colourless b) Odour No data available c) Odour Threshold No data available d) pH 6,0 - 8 at 500 g/l at 20 °C e) Melting point/freezing point Melting point/range: 10 - 12 °C - lit. f) Initial boiling point and boiling range 100 - 102 °C - lit. g) Flash point 12 °C - closed cup h) Evaporation rate No data available i) Flammability (solid, gas) No data available j) Upper/lower Upper explosion limit: 22 %(V) flammability or explosive limits Lower explosion limit: 2 %(V) k) Vapour pressure 36 hPa at 20 °C 53 hPa at 25,20 °C l) Vapour density 3,04 - (Air = 1.0) m) Relative density 1,034 g/cm3 at 25 °C n) Water solubility completely miscible o) Partition coefficient: n-octanol/water log Pow: -0,27 p) Auto-ignition temperature 190,55 °C q) Decomposition temperature No data available r) Viscosity No data available s) Explosive properties No data available t) Oxidizing properties No data available 9.2 Other safety information Surface tension 36,9 mN/m at 25 °C Relative vapour density 3,04 - (Air = 1.0) |
| STABILITY AND REACTIVITY | 10.1 Reactivity No data available 10.2 Chemical stability Stable under recommended storage conditions. Stable under recommended storage conditions. 10.3 Possibility of hazardous reactions No data available 10.4 Conditions to avoid Heat, flames and sparks. 10.5 Incompatible materials Oxygen, Oxidizing agents, Halogens, Reducing agents, Perchlorates., Trimethylaluminum 10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5 |
| TOXICOLOGICAL INFORMATION | 11.1 Information on toxicological effects Acute toxicity LD50 Oral - Rat - 4.200 mg/kg LC50 Inhalation - Rat - 2 h - 46.000 mg/m3 Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and Taste):Eye:Other. LD50 Dermal - Rabbit - 7.858 mg/kg Skin corrosion/irritation Skin - Human Remarks: Chronic exposure causes drying effect on the skin and eczema. Skin - Rabbit Result: No skin irritation Serious eye damage/eye irritation Eyes - Rabbit Result: Eye irritation - 24 h Respiratory or skin sensitisation No data available Germ cell mutagenicity Laboratory experiments have shown mutagenic effects. Carcinogenicity This product is or contains a component that has been reported to be possibly carcinogenic based on its IARC, ACGIH, NTP, or EPA classification. Limited evidence of carcinogenicity in animal studies IARC: 2B - Group 2B: Possibly carcinogenic to humans (1,4-Dioxane) Reproductive toxicity No data available Specific target organ toxicity - single exposure May cause respiratory irritation. Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available Additional Information RTECS: JG8225000 Nausea, Vomiting, Weakness, Dizziness, Vertigo, Headache, Sweating, loss of appetite, Kidney injury may occur., Liver injury may occur. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. |
| ECOLOGICAL INFORMATION | 12.1 Toxicity Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 985 mg/l - 96 h Toxicity to daphnia EC50 - Daphnia magna (Water flea) - 8.450 mg/l - 24 h and other aquatic invertebrates Toxicity to algae EC50 - Desmodesmus subspicatus (green algae) - > 500 mg/l - 72 h 12.2 Persistence and degradability Biodegradability Result: < 5 % - Not readily biodegradable. 12.3 Bioaccumulative potential Does not bioaccumulate. 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. 12.6 Other adverse effects No data available |
| DISPOSAL CONSIDERATIONS | 13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself. Contaminated packaging Dispose of as unused product. |
| TRANSPORT INFORMATION | 14.1 UN number ADR/RID: 1165 IMDG: 1165 IATA: 1165 14.2 UN proper shipping name ADR/RID: DIOXANE IMDG: DIOXANE IATA: Dioxane 14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3 14.4 Packaging group ADR/RID: II IMDG: II IATA: II 14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no 14.6 Special precautions for user No data available |
| REGULATORY INFORMATION | 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. REACH - Restrictions on the manufacture, placing on the market and use of certain dangerous substances, preparations and articles (Annex XVII) : REACH - Restrictions on the manufacture, placing on the market and use of certain dangerous substances, preparations and articles (Annex XVII) : 15.2 Chemical safety assessment A Chemical Safety Assessment has been carried out for this substance. |
| OTHER INFORMATION | The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only! |