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Difenacoum

ISO 17034 Reference Material

Item number680145
CAS56073-07-5
FormulaC31H24O3
Molecular weight444,52 g/mol
Quantity 1X25MG
storage conditions4 °C
CoA / MSDSRetrieve CoA
Retrieve MSDS
Difenacoum

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Catalog No./ CAS No.

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Difenacoum solution
Concentration: 100 µg/ml
Solvent: Acetonitrile

Difenacoum solution

675752
56073-07-5

1X1ML

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ISO 17034 Reference Material

Difenacoum

Difenacoum

680145
56073-07-5

1X25MG

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ISO 17034 Certified Reference Material

Difenacoum

Difenacoum

691086
56073-07-5

1X10MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 27.12.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Difenacoum
Catalog No.:680145
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION· 2.1 Classification of the substance or mixture
· Classification according to Regulation (EC) No 1272/2008
GHS06 skull and crossbones
Acute Tox. 1 H300 Fatal if swallowed.
Acute Tox. 1 H310 Fatal in contact with skin.
Acute Tox. 1 H330 Fatal if inhaled.
GHS08 health hazard
Repr. 1B H360D May damage the unborn child.
STOT RE 1 H372 Causes damage to the blood through prolonged or repeated exposure.
GHS09 environment
Aquatic Acute 1 H400 Very toxic to aquatic life.
Aquatic Chronic 1 H410 Very toxic to aquatic life with long lasting effects.
Label elements
PictogramGHS06 skull
skull
GHS08 silhouete
silhouete
GHS09 Aquatic-pollut-red
Aquatic-pollut-red
· 2.2 Label elements
· Labelling according to Regulation (EC) No 1272/2008
The substance is classified and labelled according to the CLP regulation.
· Hazard pictograms
GHS06 GHS08 GHS09
· Signal word Danger
· Hazard statements
H300+H310+H330 Fatal if swallowed, in contact with skin or if inhaled.
H360D May damage the unborn child.
H372 Causes damage to the blood through prolonged or repeated exposure.
H410 Very toxic to aquatic life with long lasting effects.
· Precautionary statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor.
P320 Specific treatment is urgent (see on this label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local/regional/national/international
regulations.
· Additional information:
Restricted to professional users.
· 2.3 Other hazards
· Results of PBT and vPvB assessment
· PBT: Not applicable.
· vPvB: Not applicable.
COMPOSITION/INFORMATION ON INGREDIENTS· 3.1 Chemical characterisation: Substances
· CAS No. Description
56073-07-5 difenacoum
· Identification number(s) None
· EC number: 259-978-4
· Index number: 607-157-00-X
· RTECS: GN4934500
FormulaC31H24O3
Molecular Weight (g/mol)444.52
CAS-No.56073-07-5
FIRST AID MEASURES· 4.1 Description of first aid measures
· General information:
Immediately remove any clothing soiled by the product.
Symptoms of poisoning may occur even after several hours; therefore medical observation for at least 48
hours after the accident is recommended.
Remove breathing equipment only after contaminated clothing has been completely removed.
In case of irregular breathing or respiratory arrest provide artificial respiration.
· After inhalation:
Supply fresh air or oxygen; call for doctor.
In case of unconsciousness place patient in recovery position for transport.
Seek immediate medical advice.
· After skin contact:
Immediately wash with water and soap and rinse thoroughly.
Seek immediate medical advice.
· After eye contact: Rinse opened eye for several minutes under running water. Then consult a doctor.
· After swallowing:
Rinse mouth. Do not induce vomiting.
Call for a doctor immediately.
· 4.2 Most important symptoms and effects, both acute and delayed No further relevant information available.
· 4.3 Indication of any immediate medical attention and special treatment needed
No further relevant information available.
FIRE-FIGHTING MEASURES· 5.1 Extinguishing media
· Suitable extinguishing agents: Use fire extinguishing methods suitable for surrounding conditions.
· 5.2 Special hazards arising from the substance or mixture
During heating or in case of fire poisonous gases are produced.
· 5.3 Advice for firefighters
· Protective equipment:
Mouth respiratory protective device.
Wear self-contained respiratory protective device.
ACCIDENTAL RELEASE MEASURES· 6.1 Personal precautions, protective equipment and emergency procedures
Mount respiratory protective device.
Avoid formation of dust.
· 6.2 Environmental precautions:
Inform respective authorities in case of seepage into water course or sewage system.
Do not allow to enter sewers/ surface or ground water.
· 6.3 Methods and material for containment and cleaning up:
Dispose of contaminated material as waste according to item 13.
Ensure adequate ventilation.
· 6.4 Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
HANDLING AND STORAGE· 7.1 Precautions for safe handling
Ensure good ventilation/extraction at the workplace.
Remove dust thoroughly.
Store in cool, dry place in tightly closed receptacles.
Open and handle receptacle with care.
· Information about fire - and explosion protection: Keep respiratory protective device available.
· 7.2 Conditions for safe storage, including any incompatibilities
· Storage:
· Requirements to be met by storerooms and receptacles:
Please refer to the manufacturers certificate for specific storage and transport temperature conditions.
Store only in the original receptacle unless other advice is given on the CoA.
Keep container in a well-ventilated place. Keep away from sources of ignition and heat.
· Information about storage in one common storage facility: Store away from foodstuffs.
· Further information about storage conditions: Keep container tightly sealed.
· 7.3 Specific end use(s) No further relevant information available.
EXPOSURE CONTROLS/PERSONAL PROTECTION· Additional information about design of technical facilities: No further data; see item 7.
· 8.1 Control parameters
· Ingredients with limit values that require monitoring at the workplace: Not required.
· Additional information: Lists used were valid at the time of SDS preparation.
· 8.2 Exposure controls
· Personal protective equipment:
· General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Avoid contact with the eyes and skin.
· Respiratory protection:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure
use self-contained respiratory protective device.
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced
· Protection of hands:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the
degradation
The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the
related standard EN374
Protective gloves
· Material of gloves
Butyl rubber, BR
Nitrile rubber, NBR
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be
observed.
· Eye protection:
Tightly sealed goggles
PHYSICAL AND CHEMICAL PROPERTIES· 9.1 Information on basic physical and chemical properties
· General Information
· Appearance:
Form: Solid
Colour: Off white
· Odour: Odourless
· Odour threshold: Not determined.
· pH-value: Not applicable.
· Change in condition
Melting point/freezing point: 215-217 °C
Initial boiling point and boiling range: Not determined.
· Flash point: Not applicable.
· Flammability (solid, gas): Not determined.
· Ignition temperature: Not determined
· Decomposition temperature: Not determined.
· Auto-ignition temperature: Not determined.
· Explosive properties: Not determined.
· Explosion limits:
Lower: Not determined.
Upper: Not determined.
· Vapour pressure: Not applicable.
· Density at 20 °C: 1.25 g/cm³
· Relative density Not determined.
· Vapour density Not applicable.
· Evaporation rate Not applicable.
· Solubility in / Miscibility with
water at 20 °C: 0.0025 g/l
· Partition coefficient: n-octanol/water: > 7.0 logP
· Viscosity:
Dynamic: Not applicable.
Kinematic: Not applicable.
· 9.2 Other information No further relevant information available.
STABILITY AND REACTIVITY· 10.1 Reactivity Stable under normal conditions.
· 10.2 Chemical stability Stable under normal conditions.
· Thermal decomposition / conditions to be avoided:
Formation of toxic gases is possible during heating or in case of fire.
· 10.3 Possibility of hazardous reactions No dangerous reactions known.
· 10.4 Conditions to avoid Heat.
· 10.5 Incompatible materials: Strong oxidizing agents.
· 10.6 Hazardous decomposition products:
Formation of toxic gases is possible during heating or in case of fire.
TOXICOLOGICAL INFORMATION· 11.1 Information on toxicological effects
· Acute toxicity
Fatal if swallowed, in contact with skin or if inhaled.
· LD/LC50 values relevant for classification:
Oral LD50 0.68 mg/kg (rat)
Dermal LD50 >50 mg/kg (rat)
1,000 mg/kg (rabbit)
· Primary irritant effect:
· Skin corrosion/irritation Based on available data, the classification criteria are not met.
· Serious eye damage/irritation Based on available data, the classification criteria are not met.
· Respiratory or skin sensitisation Based on available data, the classification criteria are not met.
· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)
Repr. 1B
· Germ cell mutagenicity Based on available data, the classification criteria are not met.
· Carcinogenicity Based on available data, the classification criteria are not met.
· Reproductive toxicity
May damage the unborn child.
· STOT-single exposure Based on available data, the classification criteria are not met.
· STOT-repeated exposure
Causes damage to the blood through prolonged or repeated exposure.
· Aspiration hazard Based on available data, the classification criteria are not met.
ECOLOGICAL INFORMATION· 12.1 Toxicity
· Aquatic toxicity:
LC50/48 0.52 mg/l (daphnia)
· 12.2 Persistence and degradability No further relevant information available.
· 12.3 Bioaccumulative potential No further relevant information available.
· 12.4 Mobility in soil No further relevant information available.
· Ecotoxicological effects:
· Remark: Very toxic for fish
· Additional ecological information:
· General notes:
Water hazard class 3 (German Regulation) (Self-assessment): extremely hazardous for water
Do not allow product to reach ground water, water course or sewage system, even in small quantities.
Danger to drinking water if even extremely small quantities leak into the ground.
Also poisonous for fish and plankton in water bodies.
Very toxic for aquatic organisms
· 12.5 Results of PBT and vPvB assessment
· PBT: Not applicable.
· vPvB: Not applicable.
· 12.6 Other adverse effects No further relevant information available.
DISPOSAL CONSIDERATIONS· 13.1 Waste treatment methods
· Recommendation
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
· European waste catalogue
Waste disposal key numbers from EWC have to be assigned depending on origin and processing.
· Uncleaned packaging:
· Recommendation: Dispose of in accordance with national regulations.
TRANSPORT INFORMATION· 14.1 UN-Number
· ADR, IMDG, IATA UN2811
· ADR 2811 TOXIC SOLID, ORGANIC, N.O.S. (difenacoum),
ENVIRONMENTALLY HAZARDOUS
· IMDG TOXIC SOLID, ORGANIC, N.O.S. (difenacoum), MARINE
POLLUTANT
· IATA TOXIC SOLID, ORGANIC, N.O.S. (difenacoum)
· 14.3 Transport hazard class(es)
· ADR, IMDG
· Class 6.1 Toxic substances.
· Label 6.1
· IATA
· Class 6.1 Toxic substances.
· Label 6.1
· 14.4 Packing group
· ADR, IMDG, IATA I
· 14.5 Environmental hazards: Environmentally hazardous substance, solid; Marine
Pollutant
· Marine pollutant: Symbol (fish and tree)
· Special marking (ADR): Symbol (fish and tree)
· 14.6 Special precautions for user Warning: Toxic substances.
· Danger code (Kemler): 66
· EMS Number: F-A,S-A
· Stowage Category B
· 14.7 Transport in bulk according to Annex II of
Marpol and the IBC Code Not applicable.
· Transport/Additional information:
· ADR
· Limited quantities (LQ) 0
· Excepted quantities (EQ) Code: E5
Maximum net quantity per inner packaging: 1 g
Maximum net quantity per outer packaging: 300 g
· Transport category 1
· Tunnel restriction code C/E
· UN "Model Regulation": UN 2 8 1 1 TOXIC SOLID, ORGANIC, N.O. S .
(DIFENACOUM) , 6 .1, I , ENVIRONMENTALLY
HAZARDOUS
REGULATORY INFORMATION· 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
· Directive 2012/18/EU
· Named dangerous substances - ANNEX I Substance is not listed.
· Seveso category
H1 ACUTE TOXIC
E1 Hazardous to the Aquatic Environment
· Qualifying quantity (tonnes) for the application of lower-tier requirements 5 t
· Qualifying quantity (tonnes) for the application of upper-tier requirements 20 t
· REGULATION (EC) No 1907/2006 ANNEX XVII Conditions of restriction: 30
· 15.2 Chemical safety assessment: A Chemical Safety Assessment has not been carried out.
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!