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Carbetamide
ISO 17034 Reference Material
| Item number | 676724 |
| CAS | 16118-49-3 |
| Formula | C12H16N2O3 |
| Molecular weight | 236,27 g/mol |
| Quantity | 1X250MG |
| storage conditions | 4 °C |
| CoA / MSDS | Retrieve CoA Retrieve MSDS |
Price | Please log in. |
Part of Product groups:
Product Variations:
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
Carbetamide solution |  | 675179 | 1X1ML | Please log in. |
ISO 17034 Reference Material |  | 676724 | 1X250MG | Please log in. |
ISO 17034 Certified Reference Material |  | 690251 | 1X100MG | Please log in. |
| Safety Data Sheet | according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 26.12.2024 |
| IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING | |
| Product name: | Carbetamide |
| Catalog No.: | 676724 |
| Relevant identified uses of the substance or mixture | Identified: Laboratory chemical uses: R&D |
| Uses advised against: | HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com |
| Emergency telephone number | HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours. |
| HAZARDS IDENTIFICATION | 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 4), H302 Carcinogenicity (Category 2), H351 Reproductive toxicity (Category 1B), H360D Long-term (chronic) aquatic hazard (Category 2), H411 |
| Label elements | |
| Pictogram | GHS07 exclam exclam GHS08 silhouete silhouete GHS09 Aquatic-pollut-red Aquatic-pollut-red |
| 2.2 Label elements Labelling according Regulation (EC) No 1272/2008 Signal Word Danger Hazard statement(s) H302 Harmful if swallowed. H351 Suspected of causing cancer. H360D May damage the unborn child. H411 Toxic to aquatic life with long lasting effects. Precautionary statement(s) P201 Obtain special instructions before use. P273 Avoid release to the environment. P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth. P308 + P313 IF exposed or concerned: Get medical advice/ attention. Supplemental Hazard Statements none Restricted to professional users. Reduced Labeling (<= 125 ml) Signal Word Danger Hazard statement(s) H351 Suspected of causing cancer. H360D May damage the unborn child. Precautionary statement(s) P201 Obtain special instructions before use. P308 + P313 IF exposed or concerned: Get medical advice/ attention. Supplemental Hazard Statements none 2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. | |
| COMPOSITION/INFORMATION ON INGREDIENTS | 3.1 Substances Synonyms : (R)-(−)-1-(Ethylcarbamoyl)ethyl N-phenylcarbamate Component: Carbetamide CAS-No. : 16118-49-3 EC-No. : 240-286-6 Classification: Acute Tox. 4; Carc. 2; Repr. 1B; Aquatic Chronic 2; H302, H351, H360D, H411 Concentration: <= 100 % |
| Formula | C12H16N2O3 |
| Molecular Weight (g/mol) | 236.27 |
| CAS-No. | 16118-49-3 |
| FIRST AID MEASURES | 4.1 Description of first-aid measures General advice Show this material safety data sheet to the doctor in attendance. If inhaled After inhalation: fresh air. Call in physician. In case of skin contact In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician. In case of eye contact After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses. If swallowed After swallowing: immediately make victim drink water (two glasses at most). Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available |
| FIRE-FIGHTING MEASURES | 5.1 Extinguishing media Suitable extinguishing media Water Foam Carbon dioxide (CO2) Dry powder Unsuitable extinguishing media For this substance/mixture no limitations of extinguishing agents are given. 5.2 Special hazards arising from the substance or mixture Carbon oxides Nitrogen oxides (NOx) Combustible. Development of hazardous combustion gases or vapours possible in the event of fire. 5.3 Advice for firefighters Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing. 5.4 Further information Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system. |
| ACCIDENTAL RELEASE MEASURES | 6.1 Personal precautions, protective equipment and emergency procedures Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8. 6.2 Environmental precautions Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area. Avoid generation of dusts. 6.4 Reference to other sections For disposal see section 13. |
| HANDLING AND STORAGE | 7.1 Precautions for safe handling Advice on safe handling Work under hood. Do not inhale substance/mixture. Hygiene measures Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Storage conditions Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons. Storage class Storage class (TRGS 510): 6.1C: Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| EXPOSURE CONTROLS/PERSONAL PROTECTION | 8.1 Control parameters Ingredients with workplace control parameters 8.2 Exposure controls Personal protective equipment Eye/face protection Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses Skin protection This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. Body Protection protective clothing Respiratory protection required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P3 The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. Control of environmental exposure Do not let product enter drains. |
| PHYSICAL AND CHEMICAL PROPERTIES | 9.1 Information on basic physical and chemical properties a) Physical state solid b) Color colorless c) Odor No data available d) Melting point/freezing point Melting point/range: 108,7 - 110,6 °C - OECD Test Guideline 102 e) Initial boiling point and boiling range 235 - 240 °C at 1.013 hPa - OECD Test Guideline 103 f) Flammability (solid, gas) No data available g) Upper/lower flammability or explosive limits No data available h) Flash point No data available i) Autoignition temperature No data available j) Decomposition temperature No data available k) pH No data available l) Viscosity Viscosity, kinematic: No data available Viscosity, dynamic: No data available m) Water solubility 3,67 g/l at 25 °C - Regulation (EC) No. 440/2008, Annex, A.6 n) Partition coefficient: n-octanol/water log Pow: 1,75 at 20 °C - OECD Test Guideline 107 - Bioaccumulation is not expected. o) Vapor pressure < 0,1 hPa at 20 °C - OECD Test Guideline 104 p) Density No data available Relative density No data available q) Relative vapor density No data available r) Particle characteristics No data available s) Explosive properties No data available t) Oxidizing properties none 9.2 Other safety information Surface tension 68,6 mN/m at 20 °C - OECD Test Guideline 115 |
| STABILITY AND REACTIVITY | 10.1 Reactivity The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed. 10.2 Chemical stability The product is chemically stable under standard ambient conditions (room temperature) . 10.3 Possibility of hazardous reactions No data available 10.4 Conditions to avoid no information available 10.5 Incompatible materials Strong oxidizing agents 10.6 Hazardous decomposition products In the event of fire: see section 5 |
| TOXICOLOGICAL INFORMATION | 11.1 Information on toxicological effects Acute toxicity LD50 Oral - Mouse - female - 1.445 mg/kg Remarks: (ECHA) Inhalation: No data available LD50 Dermal - Rabbit - > 2.000 mg/kg Remarks: (ECHA) Skin corrosion/irritation Skin - Rabbit Result: No skin irritation (OECD Test Guideline 404) Serious eye damage/eye irritation Eyes - Rabbit Result: No eye irritation (OECD Test Guideline 405) Respiratory or skin sensitization Maximization Test - Guinea pig Result: negative (OECD Test Guideline 406) Germ cell mutagenicity Test Type: Ames test Test system: Salmonella typhimurium Result: negative Remarks: (ECHA) Test Type: In vitro mammalian cell gene mutation test Test system: Mouse lymphoma test Method: OECD Test Guideline 476 Result: negative Test Type: Chromosome aberration test in vitro Test system: Human lymphocytes Method: OECD Test Guideline 473 Result: negative Test Type: Chromosome aberration test in vitro Test system: Chinese hamster ovary cells Result: negative Remarks: (ECHA) Test Type: sister chromatid exchange assay Test system: Chinese hamster ovary cells Result: negative Remarks: (ECHA) Test Type: unscheduled DNA synthesis assay Method: OECD Test Guideline 482 Result: negative Test Type: In vivo micronucleus test Species: mice Application Route: Oral Method: OECD Test Guideline 474 Result: negative Test Type: unscheduled DNA synthesis assay Species: Rat Method: OECD Test Guideline 486 Result: negative Carcinogenicity Suspected of causing cancer. Reproductive toxicity May damage the unborn child. Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available 11.2 Additional Information Endocrine disrupting properties Product: Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. RTECS: FD8900000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. |
| ECOLOGICAL INFORMATION | 12.1 Toxicity Toxicity to fish static test LC50 - Oncorhynchus mykiss (rainbow trout) - > 100 mg/l - 96 h (OECD Test Guideline 203) Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - 81 mg/l - 48 h (OECD Test Guideline 202) Toxicity to algae static test ErC50 - Navicula pelliculosa (Freshwater diatom) - 212 mg/l - 72 h (Regulation (EC) No. 440/2008, Annex, C.3) static test NOEC - Navicula pelliculosa (Freshwater diatom) - 50 mg/l - 72 h (Regulation (EC) No. 440/2008, Annex, C.3) Toxicity to fish(Chronic toxicity) NOEC - Salmo gairdneri - 32 mg/l - 21 d (OECD Test Guideline 204) Toxicity to daphnia and other aquatic invertebrates(Chronic toxicity) semi-static test NOEC - Daphnia magna (Water flea) - 1 mg/l - 21 d (OECD Test Guideline 202) 12.2 Persistence and degradability Biodegradability aerobic - Exposure time 28 d Result: 7,1 % - Not readily biodegradable. (OECD Test Guideline 301D) 12.3 Bioaccumulative potential No data available 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. 12.6 Endocrine disrupting properties Product: Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. 12.7 Other adverse effects No data available |
| DISPOSAL CONSIDERATIONS | 13.1 Waste treatment methods No data available |
| TRANSPORT INFORMATION | 14.1 UN number ADR/RID: 3077 IMDG: 3077 IATA: 3077 14.2 UN proper shipping name ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Carbetamide) IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Carbetamide) IATA: Environmentally hazardous substance, solid, n.o.s. (Carbetamide) 14.3 Transport hazard class(es) ADR/RID: 9 IMDG: 9 IATA: 9 14.4 Packaging group ADR/RID: III IMDG: III IATA: III 14.5 Environmental hazards ADR/RID: yes IMDG Marine pollutant: yes IATA: yes 14.6 Special precautions for user Tunnel restriction code : (-) Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9 |
| REGULATORY INFORMATION | 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006. Authorisations and/or restrictions on use REACH - Restrictions on the manufacture, placing on the market and use of certain dangerous substances, mixtures and articles (Annex XVII): Carbetamide National legislation Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of major-accident hazards involving dangerous substances. : ENVIRONMENTAL HAZARDS Other regulations Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable. Take note of Dir 94/33/EC on the protection of young people at work. 15.2 Chemical Safety Assessment For this product a chemical safety assessment was not carried out |
| OTHER INFORMATION | The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only! |