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Avermectin B1a
| Item number | 677788 |
| CAS | 65195-55-3 |
| Formula | C48H72O14 |
| Molecular weight | 873,08 g/mol |
| Quantity | 1X25MG |
| storage conditions | 4 °C |
| CoA / MSDS | Retrieve CoA Retrieve MSDS |
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Part of Product groups:
Product Variations:
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
8,9-Z-Avermectin B1a solution |  | 676147 | 1X1ML | Please log in. |
Avermectin B1a solution |  | 676144 | 1X1ML | Please log in. |
 | 677788 | 1X25MG | Please log in. |
| Safety Data Sheet | according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 08.09.2024 |
| IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING | |
| Product name: | Avermectin B1a |
| Catalog No.: | 677788 |
| Relevant identified uses of the substance or mixture | Identified: Laboratory chemical uses: R&D |
| Uses advised against: | HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com |
| Emergency telephone number | HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours. |
| HAZARDS IDENTIFICATION | 2.1. Classification of the substance or mixture Regulation (EC) No 1272/2008 Acute toxicity - Oral Category 2 - (H300) Acute toxicity - Dermal Category 3 - (H311) Acute toxicity - Inhalation (Dusts/Mists) Category 1 - (H330) Reproductive toxicity Category 2 - (H361) Specific target organ toxicity — repeated exposure Category 1 - (H372) Acute aquatic toxicity Category 1 - (H400) Chronic aquatic toxicity Category 1 - (H410) |
| Label elements | |
| Pictogram | GHS06 skull skull GHS08 silhouete silhouete GHS09 Aquatic-pollut-red Aquatic-pollut-red |
| 2.2. Label elements 265-610-3 Contains Avermectin B1a Signal word Danger Hazard statements H300 - Fatal if swallowed H311 - Toxic in contact with skin H330 - Fatal if inhaled H361d - Suspected of damaging the unborn child H372 - Causes damage to organs through prolonged or repeated exposure H410 - Very toxic to aquatic life with long lasting effects Precautionary Statements - EU (§28, 1272/2008) P260 - Do not breathe dust/fume/gas/mist/vapours/spray P273 - Avoid release to the environment P280 - Wear protective gloves/protective clothing/eye protection/face protection P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P310 - Immediately call a POISON CENTER or doctor P391 - Collect spillage P403 + P233 - Store in a well-ventilated place. Keep container tightly closed 2.3. Other hazards No information available. This substance does not meet the PBT/vPvB criteria of REACH, annex XIII. This product does not contain any known or suspected endocrine disruptors. | |
| COMPOSITION/INFORMATION ON INGREDIENTS | 3.1 Chemical name Avermectin B1a CAS: 65195-55-3 EC No (EU Index No): 265-610-3 Classification according to Regulation (EC) No. 1272/2008 [CLP] Acute Tox. 1 (H330) Acute Tox. 2 (H300) Acute Tox. 3 (H311) Repr. 2 (H361d) STOT RE 1 (H372) Aquatic Acute 1 (H400) Aquatic Chronic 1 (H410) Acute Toxicity Estimate No information available This product does not contain candidate substances of very high concern at a concentration >=0.1% (Regulation (EC) No. 1907/2006 (REACH), Article 59) |
| Formula | C48H72O14 |
| Molecular Weight (g/mol) | 873.08 |
| CAS-No. | 65195-55-3 |
| FIRST AID MEASURES | 4.1. Description of first aid measures General advice Immediate medical attention is required. Show this safety data sheet to the doctor in attendance. Inhalation If breathing has stopped, give artificial respiration. Get medical attention immediately. Remove to fresh air. Do not breathe dust. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. If breathing is difficult, (trained personnel should) give oxygen. Eye contact Get immediate medical advice/attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Keep eye wide open while rinsing. Skin contact Get immediate medical advice/attention. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Ingestion Get immediate medical advice/attention. Do NOT induce vomiting. Rinse mouth. Never give anything by mouth to an unconscious person. Self-protection of the first aider Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination. Do not breathe dust. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Use personal protective equipment as required. See section 8 for more information. 4.2. Most important symptoms and effects, both acute and delayed Symptoms Coughing and/ or wheezing. Difficulty in breathing. 4.3. Indication of any immediate medical attention and special treatment needed Note to doctors Treat symptomatically. |
| FIRE-FIGHTING MEASURES | 5.1. Extinguishing media Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Large Fire CAUTION: Use of water spray when fighting fire may be inefficient. Unsuitable extinguishing media Do not scatter spilled material with high pressure water streams. 5.2. Special hazards arising from the substance or mixture Specific hazards arising from the chemical No information available. 5.3. Advice for firefighters Special protective equipment and precautions for fire-fighters Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear. Use personal protection equipment. |
| ACCIDENTAL RELEASE MEASURES | 6.1. Personal precautions, protective equipment and emergency procedures Personal precautions Avoid contact with skin, eyes or clothing. Ensure adequate ventilation. Use personal protective equipment as required. Evacuate personnel to safe areas. Avoid generation of dust. Do not breathe dust. Keep people away from and upwind of spill/leak. Other information Refer to protective measures listed in Sections 7 and 8. For emergency responders Use personal protection recommended in Section 8. 6.2. Environmental precautions Environmental precautions Prevent further leakage or spillage if safe to do so. Should not be released into the environment. Do not allow to enter into soil/subsoil. Prevent product from entering drains. 6.3. Methods and material for containment and cleaning up Methods for containment Prevent further leakage or spillage if safe to do so. Methods for cleaning up Take up mechanically, placing in appropriate containers for disposal. Prevention of secondary hazards Clean contaminated objects and areas thoroughly observing environmental regulations. 6.4. Reference to other sections Reference to other sections See section 8 for more information. See section 13 for more information. |
| HANDLING AND STORAGE | 7.1. Precautions for safe handling Advice on safe handling Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin, eyes or clothing. Take off contaminated clothing and wash it before reuse. Do not breathe dust. Avoid generation of dust. In case of insufficient ventilation, wear suitable respiratory equipment. Handle product only in closed system or provide appropriate exhaust ventilation. Do not eat, drink or smoke when using this product. Remove contaminated clothing and shoes. General hygiene considerations Wash hands before breaks and immediately after handling the product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Regular cleaning of equipment, work area and clothing is recommended. Do not breathe dust. Take off contaminated clothing and wash it before reuse. Contaminated work clothing should not be allowed out of the workplace. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. 7.2. Conditions for safe storage, including any incompatibilities Storage Conditions Store locked up. Keep containers tightly closed in a dry, cool and well-ventilated place. Keep out of the reach of children. Please refer to the manufacturers certificate for specific storage and transport temperature conditions. Store only in the original receptacle unless other advice is given on the CoA. 7.3. Specific end use(s) Risk Management Methods: The information required is contained in this Safety Data Sheet. |
| EXPOSURE CONTROLS/PERSONAL PROTECTION | 8.1. Control parameters Exposure Limits This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies. Biological occupational exposure limits This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies Derived No Effect Level (DNEL) No information available. Predicted No Effect Concentration (PNEC) No information available. 8.2. Exposure controls Personal protective equipment Eye/face protection Avoid contact with eyes. Wear safety glasses with side shields (or goggles). Hand protection Wear suitable gloves. Impervious gloves. The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374. Glove material: Wear protective butyl rubber gloves Skin and body protection Long sleeved clothing. Chemical resistant apron. Wear suitable protective clothing. Respiratory protection When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. General hygiene considerations Wash hands before breaks and immediately after handling the product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Regular cleaning of equipment, work area and clothing is recommended. Do not breathe dust. Take off contaminated clothing and wash it before reuse. Contaminated work clothing should not be allowed out of the workplace. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. Environmental exposure controls Do not allow into any sewer, on the ground or into any body of water. |
| PHYSICAL AND CHEMICAL PROPERTIES | 9.1. Information on basic physical and chemical properties Physical state Solid Appearance Solid Colour off-white Odour No information available. Odour threshold No information available Property Values Melting point / freezing point 155 - 157 °C None known Initial boiling point and boiling range No data available Flammability No data available Flammability Limit in Air Upper flammability or explosive limits No data available Lower flammability or explosive limits No data available Flash point No data available Autoignition temperature No data available Decomposition temperature pH No data available pH (as aqueous solution) No data available Kinematic viscosity No data available Dynamic viscosity No data available Water solubility No data available Solubility(ies) No data available Partition coefficient No data available Vapour pressure No data available Relative density No data available Bulk density No data available Liquid Density No data available Relative vapour density No data available Particle characteristics Particle Size No information available Particle Size Distribution No information available 9.2. Other information Molecular weight 873.08 Molecular formula C48H72O14 9.2.1. Information with regards to physical hazard classes Not applicable 9.2.2. Other safety characteristics No information available |
| STABILITY AND REACTIVITY | 10.1. Reactivity Reactivity No information available. 10.2. Chemical stability Stability Stable under normal conditions. Explosion data Sensitivity to mechanical impact None. Sensitivity to static discharge None. 10.3. Possibility of hazardous reactions Possibility of hazardous reactions None under normal processing. 10.4. Conditions to avoid Conditions to avoid Excessive heat. 10.5. Incompatible materials Incompatible materials None known based on information supplied. Hazardous decomposition products None known based on information supplied. |
| TOXICOLOGICAL INFORMATION | 11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008 Information on likely routes of exposure Product Information Inhalation Specific test data for the substance or mixture is not available. Fatal if inhaled. (based on components). Eye contact Specific test data for the substance or mixture is not available. Skin contact Specific test data for the substance or mixture is not available. Toxic in contact with skin. (based on components). Ingestion Specific test data for the substance or mixture is not available. Fatal if swallowed. (based on components). Symptoms related to the physical, chemical and toxicological characteristics Symptoms Coughing and/ or wheezing. Difficulty in breathing. Numerical measures of toxicity No information available Acute toxicity Unknown acute toxicity Delayed and immediate effects as well as chronic effects from short and long-term exposure Skin corrosion/irritation Based on available data, the classification criteria are not met. Serious eye damage/eye irritation No information available. Respiratory or skin sensitisation No information available. Germ cell mutagenicity No information available. Carcinogenicity No information available. Reproductive toxicity Contains a known or suspected reproductive toxin. Classification based on data available for ingredients. Suspected of damaging fertility or the unborn child. STOT - single exposure No information available. STOT - repeated exposure Causes damage to organs through prolonged or repeated exposure. H372 - Causes damage to the following organs through prolonged or repeated exposure: nervous system. Aspiration hazard No information available. 11.2. Information on other hazards 11.2.1. Endocrine disrupting properties Endocrine disrupting properties No information available. 11.2.2. Other information Other adverse effects No information available. |
| ECOLOGICAL INFORMATION | 12.1. Toxicity Ecotoxicity Very toxic to aquatic life with long lasting effects. 12.2. Persistence and degradability Persistence and degradability No information available. 12.3. Bioaccumulative potential Bioaccumulation No information available. 12.4. Mobility in soil Mobility in soil No information available. 12.5. Results of PBT and vPvB assessment PBT and vPvB assessment No information available. 12.6. Endocrine disrupting properties Endocrine disrupting properties No information available. 12.7. Other adverse effects No information available. |
| DISPOSAL CONSIDERATIONS | 13.1. Waste treatment methods Waste from residues/unused Dispose of in accordance with local regulations. Dispose of waste in accordance with products environmental legislation. Contaminated packaging Do not reuse empty containers. |
| TRANSPORT INFORMATION | IATA 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (Avermectin B1a) 14.3 Transport hazard class(es) 6.1 14.4 Packing group I Description UN2811, Toxic solid, organic, n.o.s. (Avermectin B1a), 6.1, I 14.5 Environmental hazards Yes 14.6 Special precautions for user Special Provisions A3, A5 ERG Code 6L IMDG 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (Avermectin B1a) 14.3 Transport hazard class(es) 6.1 14.4 Packing group I Description UN2811, Toxic solid, organic, n.o.s. (Avermectin B1a), 6.1, I, Marine pollutant 14.5 Marine pollutant P Environmental hazards Yes 14.6 Special precautions for user Special Provisions 274 EmS-No F-A, S-A No information available 14.7 Maritime transport in bulk according to IMO instruments No information available RID 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (Avermectin B1a) 14.3 Transport hazard class(es) 6.1 14.4 Packing group I Description UN2811, Toxic solid, organic, n.o.s. (Avermectin B1a), 6.1, I, Environmentally Hazardous 14.5 Environmental hazards Yes 14.6 Special precautions for user Special Provisions 274, 614 Classification code T2 ADR 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (Avermectin B1a) 14.3 Transport hazard class(es) 6.1 14.4 Packing group I Description UN2811, Toxic solid, organic, n.o.s. (Avermectin B1a), 6.1, I, (C/E), Environmentally Hazardous 14.5 Environmental hazards Yes 14.6 Special precautions for user Special Provisions 274, 614 Classification code T2 Tunnel restriction code (C/E) |
| REGULATORY INFORMATION | 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture National regulations Germany Water hazard class (WGK) non-hazardous to water (nwg) European Union Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Authorizations and/or restrictions on use: This product does not contain substances subject to authorization (Regulation (EC) No. 1907/2006 (REACH), Annex XIV) This product does not contain substances subject to restriction (Regulation (EC) No. 1907/2006 (REACH), Annex XVII) DIRECTIVE (EU) 2021/1187 on the marketing and use of explosives precursors Not applicable Persistent Organic Pollutants Not applicable Dangerous substance category per Seveso Directive (2012/18/EU) H1 - ACUTE TOXIC H2 - ACUTE TOXIC E1 - Hazardous to the Aquatic Environment in Category Acute 1 or Chronic 1 Ozone-depleting substances (ODS) regulation (EC) 1005/2009 Not applicable 15.2. Chemical safety assessment Chemical Safety Report A Chemical Safety Assessment has been carried out for this substance |
| OTHER INFORMATION | The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only! |