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Bicyclopyrone

Item number689964
CAS352010-68-5
FormulaC19H20F3NO5
Molecular weight399,36 g/mol
Quantity 1X10MG
storage conditions20 °C
CoA / MSDSRetrieve CoA
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Bicyclopyrone

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Bicyclopyrone solution
Concentration: 100 µg/ml
Solvent: Acetonitrile

Bicyclopyrone solution

685212
352010-68-5

1X1ML

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Bicyclopyrone

Bicyclopyrone

689964
352010-68-5

1X10MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 08.09.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Bicyclopyrone
Catalog No.:689964
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1. Classification of the substance or mixture
Regulation (EC) No 1272/2008
Serious eye damage/eye irritation Category 2 - (H319)
Reproductive toxicity Category 1B - (H360)
Specific target organ toxicity — single exposure Category 3 - (H335)
Specific target organ toxicity — repeated exposure Category 2 - (H373)
Chronic aquatic toxicity Category 3 - (H412)
Label elements
PictogramGHS07 exclam
exclam
GHS08 silhouete
silhouete
2.2. Label elements
Contains Bicyclopyrone
Signal word
Danger
Hazard statements
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
H360 - May damage fertility or the unborn child
H373 - May cause damage to organs through prolonged or repeated exposure
H412 - Harmful to aquatic life with long lasting effects
Precautionary Statements - EU (§28, 1272/2008)
P201 - Obtain special instructions before use
P260 - Do not breathe dust/fume/gas/mist/vapours/spray
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P312 - Call a POISON CENTER or doctor if you feel unwell
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed
P501 - Dispose of contents/ container to an approved
2.3. Other hazards
Harmful to aquatic life. This substance does not meet the PBT/vPvB criteria of REACH, annex XIII. This product does not contain any known or suspected endocrine disruptors.


COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Chemical name: Bicyclopyrone
CAS: 352010-68-5
EC No (EU
Index No): 688-487-1
Classification according
to Regulation (EC) No.
1272/2008 [CLP]
Eye Irrit. 2 (H319)
Repr. 1B (H360)
STOT SE 3 (H335)
STOT RE 2 (H373)
Aquatic Chronic 3
(H412)
Full text of H- and EUH-phrases: see section 16
Acute Toxicity Estimate
No information available
This product does not contain candidate substances of very high concern at a concentration >=0.1% (Regulation (EC) No.
1907/2006 (REACH), Article 59)
FormulaC19H20F3NO5
Molecular Weight (g/mol)399.36
CAS-No.352010-68-5
FIRST AID MEASURES4.1. Description of first aid measures
General advice Show this safety data sheet to the doctor in attendance.
Inhalation Remove to fresh air. IF exposed or concerned: Get medical advice/attention.
Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
Remove contact lenses, if present and easy to do. Continue rinsing. Keep eye wide open
while rinsing. Do not rub affected area. Get medical attention if irritation develops and
persists.
Skin contact Wash skin with soap and water. In the case of skin irritation or allergic reactions see a
doctor.
Ingestion Do NOT induce vomiting. Rinse mouth. Never give anything by mouth to an unconscious
person. Call a doctor.
Self-protection of the first aider Avoid contact with skin, eyes or clothing. Wear personal protective clothing (see section 8).
4.2. Most important symptoms and effects, both acute and delayed
Symptoms May cause redness and tearing of the eyes. Burning sensation.
4.3. Indication of any immediate medical attention and special treatment needed
Note to doctors Treat symptomatically.
FIRE-FIGHTING MEASURES5.1. Extinguishing media
Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
Large Fire CAUTION: Use of water spray when fighting fire may be inefficient.
Unsuitable extinguishing media Do not scatter spilled material with high pressure water streams.
5.2. Special hazards arising from the substance or mixture
Specific hazards arising from the
chemical
No information available.
5.3. Advice for firefighters
Special protective equipment and
precautions for fire-fighters
Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear.
Use personal protection equipment.
ACCIDENTAL RELEASE MEASURES6.1. Personal precautions, protective equipment and emergency procedures
Personal precautions Ensure adequate ventilation. Use personal protective equipment as required. Evacuate
personnel to safe areas. Avoid contact with skin, eyes or clothing.
Other information Refer to protective measures listed in Sections 7 and 8.
For emergency responders Use personal protection recommended in Section 8.
6.2. Environmental precautions
Environmental precautions See Section 12 for additional Ecological Information.
6.3. Methods and material for containment and cleaning up
Methods for containment Prevent further leakage or spillage if safe to do so.
Methods for cleaning up
Take up mechanically, placing in appropriate containers for disposal.
Prevention of secondary hazards Clean contaminated objects and areas thoroughly observing environmental regulations.
6.4. Reference to other sections
Reference to other sections See section 8 for more information. See section 13 for more information.
HANDLING AND STORAGE7.1. Precautions for safe handling
Advice on safe handling Handle in accordance with good industrial hygiene and safety practice. Avoid contact with
skin, eyes or clothing. Do not eat, drink or smoke when using this product. Remove
contaminated clothing and shoes. Ensure adequate ventilation. Avoid breathing vapours or
mists. In case of insufficient ventilation, wear suitable respiratory equipment.
General hygiene considerations Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this
product. Wash hands before breaks and after work. Wear suitable gloves and eye/face
protection. Wash hands before breaks and immediately after handling the product.
7.2. Conditions for safe storage, including any incompatibilities
Storage Conditions Please refer to the manufacturers certificate for specific storage and transport temperature
conditions. Store only in the original receptacle unless other advice is given on the CoA.
Store locked up. Keep containers tightly closed in a dry, cool and well-ventilated place.
7.3. Specific end use(s)
Risk Management Methods (RMM) The information required is contained in this Safety Data Sheet.
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1. Control parameters
Exposure Limits This product, as supplied, does not contain any hazardous materials with occupational
exposure limits established by the region specific regulatory bodies.
Biological occupational exposure limits
This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific
regulatory bodies
Derived No Effect Level (DNEL) No information available.
Predicted No Effect Concentration
(PNEC)
No information available.
8.2. Exposure controls
Personal protective equipment
Eye/face protection Avoid contact with eyes. Wear safety glasses with side shields (or goggles). If splashes are
likely to occur, wear safety glasses with side-shields.
Hand protection Wear suitable gloves. The protective gloves to be used must comply with the specifications
of EC Directive 89/686/EEC and the related standard EN374. Wear protective butyl rubber
gloves . Wear protective gloves .
Skin and body protection Wear suitable protective clothing.
Respiratory protection No protective equipment is needed under normal use conditions. If exposure limits are
exceeded or irritation is experienced, ventilation and evacuation may be required.
General hygiene considerations Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this
product. Wash hands before breaks and after work. Wear suitable gloves and eye/face
protection. Wash hands before breaks and immediately after handling the product.
Environmental exposure controls Do not allow into any sewer, on the ground or into any body of water.
PHYSICAL AND CHEMICAL PROPERTIES9.1. Information on basic physical and chemical properties
Physical state Solid
Appearance Solid
Colour off-white
Odour No information available.
Odour threshold No information available
Property Values Remarks • Method
Melting point / freezing point 65.3 °C None known
Initial boiling point and boiling range489.5 °C None known
Flammability No data available None known
Flammability Limit in Air None known
Upper flammability or explosive
limits
No data available
Lower flammability or explosive
limits
No data available
Flash point 249.9 °C None known
Autoignition temperature No data available None known
Decomposition temperature None known
pH No data available None known
pH (as aqueous solution) No data available No information available
Kinematic viscosity No data available None known
Dynamic viscosity No data available None known
Water solubility No data available None known
Solubility(ies) Acetone, Ethyl acetate, Toluene
Partition coefficient -1.2 None known
Vapour pressure No data available None known
Relative density 1.503 None known
Bulk density No data available
Liquid Density No data available
Relative vapour density No data available None known
Particle characteristics
Particle Size No information available
Particle Size Distribution No information available
9.2. Other information
Molecular weight 399.37
Molecular formula C ₁₉H₂₀F ₃NO ₅
9.2.1. Information with regards to physical hazard classes
Not applicable
9.2.2. Other safety characteristics
No information available

STABILITY AND REACTIVITY10.1. Reactivity
Reactivity No information available.
10.2. Chemical stability
Stability Stable under normal conditions.
Explosion data
Sensitivity to mechanical impact None.
Sensitivity to static discharge None.
10.3. Possibility of hazardous reactions
Possibility of hazardous reactions None under normal processing.
10.4. Conditions to avoid
Conditions to avoid None known based on information supplied.
10.5. Incompatible materials
Incompatible materials None known based on information supplied.
Hazardous decomposition products None known based on information supplied.
TOXICOLOGICAL INFORMATION11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008
Information on likely routes of exposure
Product Information
Inhalation Specific test data for the substance or mixture is not available.
Eye contact Specific test data for the substance or mixture is not available. Causes serious eye irritation.
(based on components). May cause redness, itching, and pain.
Skin contact Specific test data for the substance or mixture is not available.
Ingestion Specific test data for the substance or mixture is not available. Ingestion may cause
gastrointestinal irritation, nausea, vomiting and diarrhea.
Symptoms related to the physical, chemical and toxicological characteristics
Symptoms May cause redness and tearing of the eyes.
Numerical measures of toxicity
Acute toxicity
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Skin corrosion/irritation Based on available data, the classification criteria are not met.
Serious eye damage/eye irritation Classification based on data available for ingredients. Causes serious eye irritation.
Respiratory or skin sensitisation No information available.
Germ cell mutagenicity No information available.
Carcinogenicity No information available.
Reproductive toxicity Contains a known or suspected reproductive toxin. Classification based on data available
for ingredients. May damage fertility or the unborn child.
STOT - single exposure May cause respiratory irritation.
STOT - repeated exposure May cause damage to organs through prolonged or repeated exposure.
Aspiration hazard No information available.
11.2. Information on other hazards
11.2.1. Endocrine disrupting properties
Endocrine disrupting properties No information available.
11.2.2. Other information
Other adverse effects No information available.
ECOLOGICAL INFORMATION12.1. Toxicity
Ecotoxicity Harmful to aquatic life with long lasting effects.
Crustacea
EC50: 46.7 mg/l (Daphnia
magna, 48h)
12.2. Persistence and degradability
Persistence and degradability No information available.
12.3. Bioaccumulative potential
Bioaccumulation There is no data for this product.
12.4. Mobility in soil
Mobility in soil No information available.
12.5. Results of PBT and vPvB assessment
PBT and vPvB assessment No information available.
12.6. Endocrine disrupting properties
Endocrine disrupting properties No information available.
12.7. Other adverse effects
No information available.
DISPOSAL CONSIDERATIONS13.1. Waste treatment methods
Waste from residues/unused
products
Dispose of in accordance with local regulations. Dispose of waste in accordance with
environmental legislation.
Contaminated packaging Do not reuse empty containers.
TRANSPORT INFORMATIONIATA
14.1 UN number or ID number Not regulated
14.2 UN proper shipping name Not regulated
14.3 Transport hazard class(es) Not regulated
14.4 Packing group Not regulated
14.5 Environmental hazards Not applicable
14.6 Special precautions for user
Special Provisions None
IMDG
14.1 UN number or ID number Not regulated
14.2 UN proper shipping name Not regulated
14.3 Transport hazard class(es) Not regulated
14.4 Packing group Not regulated
14.5 Marine pollutant Not applicable
14.6 Special precautions for user
Special Provisions None No information available
14.7 Maritime transport in bulk
according to IMO instruments
No information available
RID
14.1 UN number or ID number Not regulated
14.2 UN proper shipping name Not regulated
14.3 Transport hazard class(es) Not regulated
14.4 Packing group Not regulated
14.5 Environmental hazards Not applicable
14.6 Special precautions for user
Special Provisions None
ADR
14.1 UN number or ID number Not regulated
14.2 UN proper shipping name Not regulated
14.3 Transport hazard class(es) Not regulated
14.4 Packing group Not regulated
14.5 Environmental hazards Not applicable
14.6 Special precautions for user
Special Provisions
None

REGULATORY INFORMATION15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
Water hazard class (WGK) strongly hazardous to water (WGK 3)
European Union
Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents
at work.
Authorizations and/or restrictions on use:
This product does not contain substances subject to authorization (Regulation (EC) No. 1907/2006 (REACH), Annex XIV) This
product does not contain substances subject to restriction (Regulation (EC) No. 1907/2006 (REACH), Annex XVII)

DIRECTIVE (EU) 2021/1187 on the marketing and use of explosives precursors
Not applicable
Persistent Organic Pollutants
Not applicable
Ozone-depleting substances (ODS) regulation (EC) 1005/2009
Not applicable
International Inventories
TSCA Complies under research and development exemption or is regulated by a different
government agency.
DSL/NDSL Contact supplier for inventory compliance status
EINECS/ELINCS Contact supplier for inventory compliance status
ENCS Contact supplier for inventory compliance status
IECSC Contact supplier for inventory compliance status
KECL Contact supplier for inventory compliance status
PICCS Contact supplier for inventory compliance status
AIIC Contact supplier for inventory compliance status
Legend:
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
AICS - Australian Inventory of Chemical Substances
15.2. Chemical safety assessment
Chemical Safety Report A Chemical Safety Assessment is not required for this substance
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!