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Saccharin

ISO 17034 Reference Material

Item number675385
CAS81-07-2
FormulaC7H5NO3S
Molecular weight183,19 g/mol
Quantity 1X250MG
storage conditions4 °C
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Saccharin

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ISO 17034 Reference Material

Saccharin

Saccharin

675385
81-07-2

1X250MG

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Saccharin solution
Concentration: 100 µg/ml
Solvent: Acetonitrile

Saccharin solution

684352
81-07-2

1X1ML

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ISO 17034 Certified Reference Material

Saccharin

Saccharin

690733
81-07-2

1X100MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 18.11.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Saccharin
Catalog No.:675385
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
Label elements
Pictogram
2.2 Label elements
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Synonyms : 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide
2-Sulfobenzoic acid imide
o-Benzoic sulfimide
Formula : C7H5NO3S Molecular weight : 183,18 g/mol
CAS-No. : 81-07-2
EC-No. : 201-321-0
No components need to be disclosed according to the applicable regulations
FormulaC7H5NO3S
Molecular Weight (g/mol)183.19
CAS-No.81-07-2
FIRST AID MEASURES4.1 Description of first aid measures
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
In case of skin contact
Wash off with soap and plenty of water.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx), Sulphur oxides
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
no data available
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing vapours, mist or gas.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
protection.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
7.3 Specific end use(s)
A part from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
General industrial hygiene practice.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards
such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
Choose body protection in relation to its type, to the concentration and amount of dangerous
substances, and to the specific work-place., The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Respiratory protection is not required. Where protection from nuisance levels of dusts are desired,
use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Do not let product enter drains.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: amorphous
Colour: colourless
b) Odour odourless
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing
point
Melting point/range: 226 - 229 °C - lit.
f) Initial boiling point and
boiling range
388,76 °C
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower
flammability or
explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility 39 g/l at 23 °C - soluble
o) Partition coefficient: noctanol/
water
log Pow: 5,9 at 23 °C
p) Auto-ignition
temperature
No data available
q) Decomposition
temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available 9.2 Other safety information
Bulk density 1,15 kg/m3 at 23 °C
Solubility in other
solvents
Methanol 39 g/l at 23 °C - soluble
Ether 14 g/l at 23 °C - soluble
STABILITY AND REACTIVITY10.1 Reactivity
no data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
no data available
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Other decomposition products - no data available
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Mouse - 17.000 mg/kg
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitisation
in vivo assay - Mouse
Did not cause sensitisation on laboratory animals.
Germ cell mutagenicity
reverse mutation assay
S. typhimurium
Result: negative
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
Repeated dose
toxicity
Mouse - male and female - Oral - LOAEL : 1.000 mg/kg
RTECS: DE4200000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
ECOLOGICAL INFORMATION12.1 Toxicity
no data available
12.2 Persistence and degradability
no data available
12.3 Bioaccumulative potential
no data available
12.4 Mobility in soil
no data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Other adverse effects
no data available
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product
TRANSPORT INFORMATION14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
no data available
REGULATORY INFORMATIONThis safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!