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Hesperidin

Item number689783
CAS520-26-3
FormulaC28H34O15
Molecular weight610,56 g/mol
Quantity 1X250MG
storage conditions20 °C
CoA / MSDSRetrieve CoA
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Hesperidin

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Hesperidin

Hesperidin

689783
520-26-3

1X250MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 22.12.2024
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Hesperidin
Catalog No.:689783
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
Label elements
Pictogram
2.2 Label elements
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
2.3 Other hazards - none
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Synonyms : Hesperetin 7-rhamnoglucoside
Hesperitin-7-rutinoside
Formula : C28H34O15
Molecular weight : 610,56 g/mol
CAS-No. : 520-26-3
EC-No. : 208-288-1
No components need to be disclosed according to the applicable regulations.
FormulaC28H34O15
Molecular Weight (g/mol)610.56
CAS-No.520-26-3
FIRST AID MEASURES4.1 Description of first aid measures
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
In case of skin contact
Wash off with soap and plenty of water.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing vapours, mist or gas.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature 2 - 8 °C
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
General industrial hygiene practice.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching gloves outer surface) to avoid skin contact
with this product. Dispose of contaminated gloves after use in accordance with
applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU)
2016/425 and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail
sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which
differ from EN 374, contact the supplier of the CE approved gloves. This
recommendation is advisory only and must be evaluated by an industrial hygienist
and safety officer familiar with the specific situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use
scenario.
Body Protection
Choose body protection in relation to its type, to the concentration and amount of
dangerous substances, and to the specific work-place., The type of protective
equipment must be selected according to the concentration and amount of the
dangerous substance at the specific workplace.
Respiratory protection
Respiratory protection is not required. Where protection from nuisance levels of
dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use
respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Do not let product enter drains.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: powder
Colour: light brown
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting
point/freezing point
Melting point/range: 250 - 255 °C
f) Initial boiling point
and boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid,
gas)
No data available
j) Upper/lower
flammability or
explosive limits
No data available
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility No data available
o) Partition coefficient: No data available
n-octanol/water
p) Auto-ignition
temperature
No data available
q) Decomposition
temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available
STABILITY AND REACTIVITY10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides
Other decomposition products - No data available
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - female - > 2.000 mg/kg
(OECD Test Guideline 420)
LC50 Inhalation - Rat - male and female - 4 h - > 5,04 mg/l
(Regulation (EC) No. 440/2008, Annex, B.2)
Skin corrosion/irritation
Skin - In vitro study
Result: No skin irritation - 15 min
(OECD Test Guideline 439)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation - 72 h
(OECD Test Guideline 405)
Eyes - Bovine cornea
Result: No eye irritation - 4 h
(OECD Test Guideline 437)
Respiratory or skin sensitisation
Local lymph node assay (LLNA) - Mouse
Result: negative
(OECD Test Guideline 429)
Germ cell mutagenicity
Ames test
S. typhimurium
Result: negative
(ECHA)
Rat - male - Other cell types
Result: negative
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
Repeated dose toxicity - Rat - male - Oral - 200 Days - No observed adverse effect level -
750 mg/kg
(ECHA)
RTECS: Not available
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
ECOLOGICAL INFORMATION12.1 Toxicity
Toxicity to fish static test LC50 - Oncorhynchus mykiss (rainbow trout) - > 100 mg/l
- 96 h
(OECD Test Guideline 203)
Remarks: (in analogy to similar products)
Toxicity to daphnia
and other aquatic
invertebrates
static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h
(OECD Test Guideline 202)
Remarks: (in analogy to similar products)
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - > 100
mg/l - 72 h
(OECD Test Guideline 201)
Remarks: (in analogy to similar products)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 80 % - Readily biodegradable.
(OECD Test Guideline 301B)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
12.6 Other adverse effects
No data available
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.
TRANSPORT INFORMATION14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
REGULATORY INFORMATION15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
International Chemical Weapons Convention
(CWC) Schedules of Toxic Chemicals and
Precursors
: Neither banned nor restricted
Restrictions on the marketing and use of certain
dangerous substances and preparations
: Neither banned nor restricted
Regulation (EC) No 649/2012 of the European
Parliament and the Council concerning the
export and import of dangerous chemicals
: Neither banned nor restricted
REACH - Candidate List of Substances of Very
High Concern for Authorisation (Article 59).
: This product does not contain
substances of very high concern
(Regulation (EC) No
1907/2006 (REACH), Article 57).
15.2 Chemical safety assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!