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Dimethyl isophthalate

Item number682635
CAS1459-93-4
FormulaC10H10O4
Molecular weight194,18 g/mol
Quantity 1X1000MG
storage conditions20 °C
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Dimethyl isophthalate

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Dimethyl isophthalate

Dimethyl isophthalate

682635
1459-93-4

1X1000MG

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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 15.01.2025
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Dimethyl isophthalate
Catalog No.:682635
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Am Wieseneck 7

04451 Cunnersdorf
Deutschland


Tel. +49 34291 3372-36
Fax. +49 34291 3372-39
contact@hpc-standards.com
Emergency telephone numberHPC Standards Tel. +49 34291 3372-36
This number is only available during office hours.
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Eye irritation, (Category 2)
H319: Causes serious eye irritation.
Label elements
PictogramGHS07 exclam
exclam
2.2 Label elements
Labeling according Regulation (EC) No 1272/2008
Signal Word Warning
Hazard Statements
H319 Causes serious eye irritation.
Precautionary Statements
P264 Wash skin thoroughly after handling.
P280 Wear eye protection/ face protection.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
Supplemental Hazard
Statements
none
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
Ecological information:
The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Toxicological information:
The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
EC-No. : 215-951-9
Component:
dimethyl isophthalate
Classification:
Eye Irrit. 2; H319
For the full text of the H-Statements mentioned in this Section, see Section 16.
FormulaC10H10O4
Molecular Weight (g/mol)194.18
CAS-No.1459-93-4
FIRST AID MEASURES4.1 Description of first-aid measures
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact
lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a
physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labeling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.
5.4 Further information
Prevent fire extinguishing water from contaminating surface water or the ground water
system.
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact.
Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures,
consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid
generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Dry.
Storage class
Storage class (TRGS 510): 11: Combustible Solids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN 16523-1 please
contact the supplier of CE-approved gloves.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Body Protection
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following
standards: DIN EN 143, DIN 14387 and other accompanying standards relating to
the used respiratory protection system.
Recommended Filter type: Filter type P2
The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Physical state flakes
b) Color white
c) Odor No data available
d) Melting
point/freezing point
Melting point/range: 64 - 68 °C - lit.
e) Initial boiling point
and boiling range
282 °C at 1.013 hPa - (ECHA)
f) Flammability (solid,
gas)
No data available
g) Upper/lower
flammability or
explosive limits
No data available
h) Flash point 173 °C - closed cup
i) Autoignition
temperature
No data available
j) Decomposition
temperature
No data available
k) pH No data available
l) Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: 2,14 mPa.s at 99 °C
m) Water solubility 0,29 g/l at 20 °C - OECD Test Guideline 105- partly soluble
n) Partition coefficient:
n-octanol/water
log Pow: 2,1 at 20 °C - Bioaccumulation is not expected.
o) Vapor pressure 125 hPa at 208 °C
p) Density 1,194 g/cm3 at 20 °C
Relative density 1,194 at 20 °C
q) Relative vapor
density
r) Particle
characteristics
No data available
s) Explosive properties Not classified as explosive.
t) Oxidizing properties none
9.2 Other safety information
No data available
STABILITY AND REACTIVITY10.1 Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
The following applies in general to flammable organic substances and mixtures: in
correspondingly fine distribution, when whirled up a dust explosion potential may generally
be assumed.
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
no information available
10.4 Conditions to avoid
Strong heating.
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - female - > 2.000 mg/kg
(OECD Test Guideline 423)
Inhalation: No data available
LD50 Dermal - Rat - male and female - > 2.000 mg/kg
(OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 4 h
(OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye irritation.
(OECD Test Guideline 405)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative
(OECD Test Guideline 406)
Local lymph node assay (LLNA) - Mouse
Result: negative
(OECD Test Guideline 429)
Germ cell mutagenicity
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Human lymphocytes
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 473
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Mouse lymphoma test
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Carcinogenicity
No data available
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information
Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain
components considered to have endocrine
disrupting properties according to REACH Article
57(f) or Commission Delegated regulation (EU)
2017/2100 or Commission Regulation (EU)
2018/605 at levels of 0.1% or higher.
RTECS: NT2540000
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
When dusts are generated:
After skin contact: Irritations.After eye contact: Irritations.
After swallowing: irritations of mucous membranes in the mouth, pharynx, esophagus
and gastrointestinal tract.
ECOLOGICAL INFORMATION12.1 Toxicity
Toxicity to fish static test LC50 - Oncorhynchus mykiss (rainbow trout) - 21,6 mg/l
- 96 h
(OECD Test Guideline 203)
static test NOEC - Oncorhynchus mykiss (rainbow trout) - 6,3 mg/l - 96 h
(OECD Test Guideline 203)
Toxicity to daphnia
and other aquatic
invertebrates
static test EC50 - Daphnia magna (Water flea) - 50 mg/l - 48 h
(OECD Test Guideline 202)
static test NOEC - Daphnia magna (Water flea) - 39,9 mg/l - 48 h
(OECD Test Guideline 202)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) -
13,9 mg/l - 72 h
(OECD Test Guideline 201)
static test NOEC - Pseudokirchneriella subcapitata (green algae) -
4,43 mg/l - 72 h
(OECD Test Guideline 201)
Toxicity to bacteria NOEC - activated sludge - 100 mg/l - 336 h
Remarks: (ECHA)
12.2 Persistence and degradability
Biodegradability Result: 96 - 100 % - Readily biodegradable.
(OECD Test Guideline 301C)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components
considered to have endocrine disrupting properties
according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.
12.7 Other adverse effects
No data available
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
No data available
TRANSPORT INFORMATION14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
Further information
Not classified as dangerous in the meaning of transport regulations.
REGULATORY INFORMATION15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
Other regulations
Take note of Dir 94/33/EC on the protection of young people at work.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out.
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!