New user? / Forgot your password?
0 Item | 0,00 €
Need NMR solvents or supplies? Click here and check out our ARMAR Isotopes catalog!
Caffeine
ISO 17034 Reference Material
| Item number | 677300 |
| CAS | 58-08-2 |
| Formula | C8H10N4O2 |
| Molecular weight | 194,19 g/mol |
| Quantity | 1X250MG |
| storage conditions | 4 °C |
| CoA / MSDS | Retrieve CoA Retrieve MSDS |
Price | Please log in. |
Part of Product groups:
Product Variations:
Product | Catalog No./ CAS No. | Quantity | Price | |
|---|---|---|---|---|
 | 680424 | 1X10MG | Please log in. | |
13C3-Caffeine solution |  | 681491 | 1X1ML | Please log in. |
ISO 17034 Reference Material |  | 677300 | 1X250MG | Please log in. |
Caffeine solution |  | 677301 | 1X1ML | Please log in. |
ISO 17034 Certified Reference Material |  | 692337 | 1X100MG | Please log in. |
| Safety Data Sheet | according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate 21.12.2024 |
| IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING | |
| Product name: | Caffeine |
| Catalog No.: | 677300 |
| Relevant identified uses of the substance or mixture | Identified: Laboratory chemical uses: R&D |
| Uses advised against: | HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com |
| Emergency telephone number | HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours. |
| HAZARDS IDENTIFICATION | 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 4), H302 Classification according to EU Directives 67/548/EEC or 1999/45/EC Xn Harmful R22 |
| Label elements | |
| Pictogram | GHS07 exclam exclam |
| 2.2 Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal word Warning Hazard statement(s) H302 Harmful if swallowed. Precautionary statement(s) none Supplemental Hazard None Statements 2.3 Other hazards - none | |
| COMPOSITION/INFORMATION ON INGREDIENTS | 3.1 Substances Synonyms : 1,3,7-Trimethylxanthine Formula : C8H10N4O2 Molecular Weight : 194,19 g/mol CAS-No. : 58-08-2 EC-No. : 200-362-1 Index-No. : 613-086-00-5 Hazardous ingredients according to Regulation (EC) No 1272/2008 Component Classification Concentration Caffeine CAS-No. EC-No. Index-No. 58-08-2 200-362-1 613-086-00-5 Acute Tox. 4; H302 <= 100 % Hazardous ingredients according to Directive 1999/45/EC Component Classification Concentration Caffeine CAS-No. EC-No. Index-No. 58-08-2 200-362-1 613-086-00-5 Xn, R22 <= 100 % |
| Formula | C8H10N4O2 |
| Molecular Weight (g/mol) | 194.19 |
| CAS-No. | 58-08-2 |
| FIRST AID MEASURES | 4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Flush eyes with water as a precaution. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed no data available |
| FIRE-FIGHTING MEASURES | 5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. 5.2 Special hazards arising from the substance or mixture no data available 5.3 Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. 5.4 Further information no data available |
| ACCIDENTAL RELEASE MEASURES | 6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Avoid breathing dust. For personal protection see section 8. 6.2 Environmental precautions Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. 6.4 Reference to other sections For disposal see section 13. |
| HANDLING AND STORAGE | 7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| EXPOSURE CONTROLS/PERSONAL PROTECTION | 8.1 Control parameters Components with workplace control parameters 8.2 Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Do not let product enter drains. |
| PHYSICAL AND CHEMICAL PROPERTIES | 9.1 Information on basic physical and chemical properties a) Appearance Form: crystalline, powder Colour: white b) Odour odourless c) Odour Threshold no data available d) pH 5,5 - 6,5 at 10 g/l at 20 °C e) Melting point/freezing point Melting point/range: 234 - 236,5 °C - lit. f) Initial boiling point and boiling range no data available g) Flash point no data available h) Evapouration rate no data available i) Flammability (solid, gas) no data available j) Upper/lower flammability or explosive limits no data available k) Vapour pressure 20 hPa at 89 °C l) Vapour density no data available m) Relative density 1,230 g/cm3 at 18 °C n) Water solubility 18,7 g/l at 16 °C o) Partition coefficient: noctanol/ water log Pow: -0,091 at 23 °C p) Auto-ignition temperature no data available q) Decomposition temperature no data available r) Viscosity no data available s) Explosive properties no data available t) Oxidizing properties no data available 9.2 Other safety information Bulk density 220 kg/m3 Dissociation constant 10,4 at 40 °C |
| STABILITY AND REACTIVITY | 10.1 Reactivity no data available 10.2 Chemical stability Stable under recommended storage conditions. 10.3 Possibility of hazardous reactions no data available 10.4 Conditions to avoid no data available 10.5 Incompatible materials Strong oxidizing agents 10.6 Hazardous decomposition products Other decomposition products - no data available In the event of fire: see section 5 |
| TOXICOLOGICAL INFORMATION | 11.1 Information on toxicological effects Acute toxicity LD50 Oral - rat - male and female - 367,7 mg/kg (OECD Test Guideline 401) LC50 Inhalation - rat - male and female - 4,94 mg/l (Calculation method) LD50 Dermal - rat - male and female - > 2.000 mg/kg Skin corrosion/irritation Skin - rabbit Result: No skin irritation (OECD Test Guideline 404) Serious eye damage/eye irritation Eyes - rabbit Result: No eye irritation (OECD Test Guideline 405) Respiratory or skin sensitisation - mouse Result: Did not cause sensitisation on laboratory animals. Germ cell mutagenicity rat Kidney Micronucleus test mouse Micronucleus test Carcinogenicity IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Caffeine) Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Additional Information RTECS: EV6475000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Liver - Irregularities - Based on Human Evidence |
| ECOLOGICAL INFORMATION | 12.1 Toxicity Toxicity to fish LC50 - Leuciscus idus (Golden orfe) - 87 mg/l - 96 h Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - 182 mg/l - 48 h (DIN 38412) Toxicity to algae static test - Desmodesmus subspicatus (green algae) - > 100 mg/l - 72 h (OECD Test Guideline 201) 12.2 Persistence and degradability no data available 12.3 Bioaccumulative potential no data available 12.4 Mobility in soil no data available 12.5 Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted 12.6 Other adverse effects no data available |
| DISPOSAL CONSIDERATIONS | 13.1 Waste treatment methods Product Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product. |
| TRANSPORT INFORMATION | 14.1 UN number ADR/RID: - IMDG: - IATA: - 14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods 14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: - 14.4 Packaging group ADR/RID: - IMDG: - IATA: - 14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no 14.6 Special precautions for user no data available |
| REGULATORY INFORMATION | This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture no data available 15.2 Chemical Safety Assessment For this product a chemical safety assessment was not carried out |
| OTHER INFORMATION | The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only! |